Metastatic pancreatic adenocarcinoma treated with liposomal irinotecan in combination with 5-fluorouracil and leucovorin as a II line chemotherapy

• Authors: Leszek Kraj , Maciej Gryziak , Ewa Żurawińska-Grzelka , Krzysztof Woźniak
• Languages of publication: EN

Abstracts

EN

The paper presents a case of a 54-year-old man with pancreatic tumor and intraperitoneal dissemination. The patient received treatment with gemcitabine in combination with nab-paclitaxel. After 18 months, the disease progressed, therefore the line of treatment was applied in the form of liposomal irinotecan with 5-FU/LV. This therapy provided progression-free survival for 7 months. The obtained results are better than the median progression-free survival obtained in the studies. This case demonstrates that liposomal irinotecan in the treatment of stage IV disease in patients progressing after gemcitabine opens up new treatment options.

Keywords

EN

II line chemotherapy; leucovorin; liposomal irinotecan; overall survival; pancreatic cancer; peripheral polyneuropathy

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Education
• Journal: OncoReview
• Year: 2021
• Volume: 11
• Issue: 2
• Pages: 44-47

Contributors

author

Leszek Kraj

• Clinic of Oncology, The Medical University of Warsaw

author

Maciej Gryziak

• Clinic of Oncology, The Medical University of Warsaw

author

Ewa Żurawińska-Grzelka

• Clinic of Oncology, The Medical University of Warsaw

author

Krzysztof Woźniak

• Clinic of Oncology, The Medical University of Warsaw

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• Document Type: article