INFLUENCE OF HYDROPHILIC POLYMERS ON THE PROPERTIES OF GYNECOLOGICAL POWDERS CONTAINING LACTIC ACID COMPLEXED WITH CHITOSAN

• Authors: Katarzyna Małolepsza-Jarmołowska
• Languages of publication: EN

Abstracts

EN

Tested impact of polyvinyl alcohol, dextrane and calcium alginate for the properties of the powders containing poloxamer 407 and lactic acid complexed with chitosan. For researches was prepared formulations with different pH and rheological properties. The thermosensitive gels obtained from thermosensitive powders possess the work of adhesion with different values. The researches revealed that the dynamic viscosity of the gels obtained from powders is high. A wide range of pH of the thermosensitive gels allows the selection of the optimum formulation. The gels obtained from the powders containing polyvinyl alcohol or dextrane or calcium alginate were characterized by the specific dynamic viscosity. The researches demonstrated that the methylcellulose with different values of the viscosity with poloxamer 407 significantly affect the adhesive properties of thermosensitive hydrophilic gels obtained from powders.

Keywords

EN

anti-inflammatory drugs; lactic acid complexed with chitosan; physiological environment of vagina; thermosensitive hydrophilic powders passing gels; vaginal infections; vaginal mucosa

• Publisher: Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
• Journal: Progress on Chemistry and Application of Chitin and its Derivatives
• Year: 2015
• Volume: 20
• Pages: 195-203

Contributors

author

Katarzyna Małolepsza-Jarmołowska

• Faculty of Pharmacy, The “Silesian Piasts” memorial Medical University of Wroclaw, ul. Borowska 211A, 50-556 Wrocław, Borowska 211A Street, Poland

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• Document Type: article