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Journal
2020 | 7 | 2 | 103-107
Article title

Sleep apnea and dry eye: how sleep apnea affects the eye surface

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EN
Abstracts
EN
Purpose: The purpose of this study was to determine the presence of dry eye disease and possible treatment options in patients with obstructive sleep apnea and continuous positive airway pressure. Materials and methods: A total of 72 patients (midlife age) with obstructive sleep apnea and continuous positive airway pressure therapy underwent a comprehensive eye examination. Fluorescein staining of the anterior ocular surface and tear break-up test were performed. All of the patients who were diagnosed with dry eye disease received personalized therapy. One month later, re-examination was performed using the same methodology and clinical settings. Results: On the first examination, 48 of 72 patients (66.67%) were diagnosed with dry eye disease. Floppy eyelid syndrome was reported in 26 patients (54.17%) with dry eye disease. The treatment of 40 patients included artificial tear supplements during the day in combination with high-viscosity topical gels before bedtime. In more severe cases (10.42% of all participants), the application of bandage contact lenses for 3 months was necessary. Because of excessive lid laxity, surgical reconstruction of the eyelids was performed in three patients (6.25%). Conclusions: A multidisciplinary approach is essential for obstructive sleep apnea. Practitioners from different specialties must be well acquainted with risk factors, signs, and symptoms. The early detection of dry eye disease in patients with obstructive sleep apnea and appropriate treatments are important for improving the quality of life in this patient group.
Discipline
Publisher

Journal
Year
Volume
7
Issue
2
Pages
103-107
Physical description
Contributors
  • Department of Ophthalmology and Visual Sciences, Faculty of Medicine, Medical University of Varna
  • Department of Ophthalmology and Visual Sciences, Faculty of Medicine, Medical University of Varna, cgrupcheva@gmail.com
  • Department of Ophthalmology and Visual Sciences, Faculty of Medicine, Medical University of Varna
  • Department of Ophthalmology and Visual Sciences, Faculty of Medicine, Medical University of Varna
  • Department of Ophthalmology and Visual Sciences, Faculty of Medicine, Medical University of Varna
References
  • 1. Zhang X, M VJ, Qu Y et al. Dry Eye Management: Targeting the Ocular Surface Microenvironment. Int J Mol Sci. 2017; 18(7). https://doi.org/10.3390/ijms18071398.
  • 2. Messmer EM. The pathophysiology, diagnosis, and treatment of dry eye disease. Dtsch Arztebl Int. 2015; 112(5): 71-81; quiz 82. https://doi.org/10.3238/arztebl.2015.0071.
  • 3. Javadi MA, Feizi S. Dry Eye Syndrome. J Ophthalmic Vis Res. 2011; 6(3): 192-8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306104.
  • 4. Lemp MA, Foulks GN. The Definition & Classification of Dry Eye Disease Guidelines from the 2007 International Dry Eye Workshop. Ocul Surf. 2008. https://www.tearfilm.org/pdfs/OM – Definition & Classification.pdf.
  • 5. Report of the International Dry Eye Workshop (DEWS). Ocul Surf. 2007; 5(2). www.theocularsurface.com.
  • 6. Holly FJ, Lemp MA. Tear physiology and dry eyes. Surv Ophthalmol. 22(2): 69-87. https://doi.org/10.1016/0039-6257(77)90087-x.
  • 7. Sateia MJ. International Classification of Sleep Disorders-Third Edition. Chest. 2014; 146(5): 1387-94. https://doi.org/10.1378/CHEST.14-0970.
  • 8. Lévy P, Kohler M, McNicholas WT et al. Obstructive sleep apnoea syndrome. Nature Reviews Disease Primers. 2015; 1(1): 15015. https://doi.org/10.1038/nrdp.2015.15.
  • 9. Bachour A, Maasilta P. Mouth Breathing Compromises Adherence to Nasal Continuous Positive Airway Pressure Therapy. Chest. 2004; 126(4): 1248-54. https://doi.org/10.1378/chest.126.4.1248.
  • 10. Pépin JL, Leger P, Veale D. Side Effects of Nasal Continuous Positive Airway Pressure in Sleep Apnea Syndrome. Chest. 1995; 107(2): 375-81. https://doi.org/10.1378/chest.107.2.375.
  • 11. McNab AA. The eye and sleep apnea. Sleep Med Rev. 2007; 11(4): 269-76. https://doi.org/10.1016/j.smrv.2007.03.006.
  • 12. Stein JD, Kim DS, Mundy KM et al. The association between glaucomatous and other causes of optic neuropathy and sleep apnea. Am J Ophthalmol. 2011; 152(6): 989-98.e3. https://doi.org/10.1016/j.ajo.2011.04.030.
  • 13. Morsy NE, Amani BE, Magda AA et al. Prevalence and Predictors of Ocular Complications in Obstructive Sleep Apnea Patients: A Cross-sectional Case-control Study. Open Resp Med J. 2019; 13: 19-30. https://doi.org/10.2174/1874306401913010019.
  • 14. Arda H, Birer, S Aksu M et al. Obstructive sleep apnoea prevalence in non-arteritic anterior ischaemic optic neuropathy. Br J Ophthalmol. 2013; 97(2): 206-9. https://doi.org/10.1136/bjophthalmol-2012-302598.
  • 15. Sullivan BD, Crews LA, Messmer EM et al. Correlations between commonly used objective signs and symptoms for the diagnosis of dry eye disease: clinical implications. Acta Ophthalmol. 2014; 92(2): 161-6. https://doi.org/10.1111/aos.12012.
  • 16. Craig JP, Nichols KK, Akpek EK et al. TFOS DEWS II Definition and Classification Report. Ocul Surf. 2017; 15(3): 276-83. https://doi.org/10.1016/j.jtos.2017.05.008.
  • 17. Hashemi H, Khabazkhoob M, Kheirkhah A et al. Prevalence of dry eye syndrome in an adult population. Clin Exp Ophthalmol. 2014; 42(3): 242-8. https://doi.org/10.1111/ceo.12183.
  • 18. Mertzanis P, Abetz L, Rajagopalan K et al. The relative burden of dry eye in patients’ lives: comparisons to a U.S. normative sample. Investe Ophthalmol Vis Sci. 2005; 46(1): 46-50. https://doi.org/10.1167/iovs.03-0915.
  • 19. Friedman NJ. Impact of dry eye disease and treatment on quality of life. Curr Opin Ophthalmol. 2010; 21(4): 1. https://doi.org/10.1097/ICU.0b013e32833a8c15.
  • 20. Moss SE, Klein R, Klein BEK. Prevalence of and Risk Factors for Dry Eye Syndrome. Arch Ophthalmol. 2000; 118(9): 1264. https://doi.org/10.1001/archopht.118.9.1264.
  • 21. Pritchard N, Fonn D, Brazeau D. Discontinuation of contact lens wear: a survey. Int Contact Lens Clin. 1999; 26(6): 157-62. https://doi.org/10.1016/s0892-8967(01)00040-2.
  • 22. Akkaya S, Atakan T, Acikalin B et al. Effects of long-term computer use on eye dryness. North Clin Istanb. 2018; 5(4): 319-22. https://doi.org/10.14744/nci.2017.54036.
  • 23. Rolando M, Iester M, Macrí A et al. Low Spatial-Contrast Sensitivity in Dry Eyes. Cornea. 1998; 17(4): 376. https://doi.org/10.1097/00003226-199807000-00006.
  • 24. Alves M, Novaes P, Morraye M de A et al. Is dry eye an environmental disease? Arq Bras Oftalmol. 2014; 77(3): 193-200. https://doi.org/10.5935/0004-2749.20140050.
  • 25. Santos M, Hofmann RJ. Ocular Manifestations of Obstructive Sleep Apnea. J Clin Sleep Med. 2017; 13(11): 1345-8. https://doi.org/10.5664/JCSM.6812.
  • 26. Hayirci E, Yagci A, Palamar M et al. The Effect of Continuous Positive Airway Pressure Treatment for Obstructive Sleep Apnea Syndrome on the Ocular Surface. Cornea. 2012; 31(6): 604-8. https://doi.org/10.1097/ICO.0b013e31824a2040.
  • 27. Şimşek C, Doğru, M, Kojima T et al. Current Management and Treatment of Dry Eye Disease. Turk J Ophthalmol. 2018; 48(6): 309. https://doi.org/10.4274/TJO.69320.
  • 28. Karaca EE, Akçam HT, Uzun F et al. Evaluation of Ocular Surface Health in Patients with Obstructive Sleep Apnea Syndrome. Turk J Ophthalmol. 2016; 46(3): 104. https://doi.org/10.4274/TJO.57778.
  • 29. Acar M, Firat H, Acar U et al. Ocular surface assessment in patients with obstructive sleep apnea-hypopnea syndrome. Sleep Breat. 2013; 17(2): 583-8. https://doi.org/10.1007/s11325-012-0724-0.
  • 30. Huon LK, Liu SYC, Camacho M et al. The association between ophthalmologic diseases and obstructive sleep apnea: a systematic review and meta-analysis. Sleep Breath. 2016; 20(4): 1145-54. https://doi.org/10.1007/s11325-016-1358-4.
  • 31. Dhillon S, Shapirpo CM, Flanagan J. Sleep-disordered breathing and effects on ocular health. Can J Ophthalmol. 2007; 42(2): 238-43. https://doi.org/10.3129/can j ophthalmol.i07-029.
Document Type
undetermined
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Identifiers
YADDA identifier
bwmeta1.element.psjd-53580f9f-9965-46d9-b39a-310a9ae652fb
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