Microorganisms are ubiquitous and are important area for research due to their importance in beverages, food, pharmaceuticals, and enzymes industries. Many microbial species are used in industries like- fungus, bacteria, yeast etc. They require special media to grow that should be rich in carbon, nitrogen, phosphate source, vitamins etc. Apart from this many other components are also being used to prepare media. There are enormous amount of products that microbes provide like- antibiotics, dairy products, biopolymers, cosmetics, fermented food and beverages etc. Firstly microbes are isolated from various sources and then are screened accordingly. There are primary and secondary screening methods available that can be used. Microbial cultures need to be preserved to avoid contamination so that they can be available for further uses. In this review we are looking forward to know more about microbes and their products.