PL EN


Preferences help
enabled [disable] Abstract
Number of results
2017 | 75 | 64-72
Article title

Instrumental techniques used in the analysis of exhaled air

Content
Title variants
Languages of publication
EN
Abstracts
EN
Exhaled air composition changes depending on the health status of the patient, making it possible to use breath analysis for diagnosis and monitoring purposes. Despite the fact that it is not yet used in every day medical practice, it potential application could facilitate the diagnostics of various diseases such as metabolic disorders, respiratory tract and gastrointestinal diseases. Described in this paper are different application of exhaled air analysis. Additionally, currently available techniques of sample analysis are discussed, as well as their potential advantages and disadvantages.
Year
Volume
75
Pages
64-72
Physical description
Contributors
author
  • Gdansk University of Technology, Faculty of Chemistry, Department of Analytical Chemistry, Gdansk, Poland
author
  • Gdansk University of Technology, Faculty of Chemistry, Department of Analytical Chemistry, Gdansk, Poland
author
  • Gdansk University of Technology, Faculty of Chemistry, Department of Analytical Chemistry, Gdansk, Poland
References
  • [1] D. Hill and R. Binions, Breath Analysis for Medical Diagnosis, 2012.
  • [2] A. W. Boots et al., The versatile use of exhaled volatile organic compounds in human health and disease, J. Breath Res. J. Breath Res, vol. 6, no. 6, pp. 27108–21, 271AD.
  • [3] W. Miekisch and J. K. Schubert, From highly sophisticated analytical techniques to life-saving diagnostics: Technical developments in breath analysis. 2006
  • [4] K.-H. Kim, S. A. Jahan, and E. Kabir, A review of breath analysis for diagnosis of human health, TrAC Trends Anal. Chem., vol. 33, pp. 1–8, 2012.
  • [5] Andras Bikov, Zsófia Lázár and Ildiko Horvath, Established methodological issues in electronic nose research: how far are we from using these instruments in clinical settings of breath analysis?, J. Breath Res, vol. 9, 2015
  • [6] W. Miekisch, J. K. Schubert, and G. F. E. Noeldge-Schomburg, Diagnostic potential of breath analysis—focus on volatile organic compounds. 2004
  • [7] C. Deng, J. Zhang, X. Yu, W. Zhang, and X. Zhang, Determination of acetone in human breath by gas chromatography–mass spectrometry and solid-phase microextraction with on-fiber derivatization, J. Chromatogr. B, vol. 810, no. 2, pp. 269–275, Oct. 2004.
  • [8] Kubán P. Foret F., Exhaled breath condensate: Determination of non-volatile compounds and their potential for clinical diagnosis and monitoring. A review. 2013
  • [9] A. Krilaviciute, J. A. Heiss, M. Leja, J. Kupcinskas, H. Haick, and H. Brenner, Detection of cancer through exhaled breath: a systematic review, Oncotarget, vol. 6, no. 36, 2015.
  • [10] Y. Saalberg and M. Wolff, VOC breath biomarkers in lung cancer, 2016.
  • [11] A. Christiansen et al., Ion mobility spectrometry in breath research, J. Breath Res. J. Breath Res. J. Breath Res, vol. 8, no. 8, pp. 27104–11, 271AD.
  • [12] B. Moser, F. Bodrogi, G. Eibl, M. Lechner, J. Rieder, and P. Lirk, Mass spectrometric profile of exhaled breath—field study by PTR-MS, Respir. Physiol. Neurobiol., vol. 145, pp. 295–300, 2005.
  • [13] I. Kushch et al., Determining concentration patterns of volatile compounds in exhaled breath by PTR-MS, J. Breath Res. J. Breath Res, vol. 3, no. 3, pp. 27002–15, 2009.
  • [14] P. Š. Paněl and D. Smith, Quantitative Selected Ion Flow Tube Mass Spectrometry: The Influence of Ionic Diffusion and Mass Discrimination. 2001
  • [15] A. D ’amico et al., Olfactory systems for medical applications, Sensors Actuators B, vol. 130, pp. 458–465, 2008.
  • [16] S. Dragonieri et al., An electronic nose discriminates exhaled breath of patients with untreated pulmonary sarcoidosis from controls, Respir. Med., vol. 107, pp. 1073–1078, 2013.
  • [17] R. F. Machado et al., Detection of Lung Cancer by Sensor Array Analyses of Exhaled Breath, Am. J. Respir. Crit. Care Med., vol. 171, no. 11, pp. 1286–1291, 2005.
  • [18] P. T. H. Oh Eun Hae, Song Hyun Seok, Recent advances in electronic and bioelectronic noses and their biomedical applications. 2011
  • [19] N. Fens, M. P. van der Schee, P. Brinkman, and P. J. Sterk, Exhaled breath analysis by electronic nose in airways disease. Established issues and key questions, Clin. Exp. Allergy, vol. 43, no. 7, pp. 705–715, Jul. 2013.
  • [20] L. D. Bos, P. J. Sterk, and S. J. Fowler, Breathomics in the setting of asthma and chronic obstructive pulmonary disease, 2016.
  • [21] N. Fens et al., External validation of exhaled breath profiling using an electronic nose in the discrimination of asthma with fixed airways obstruction and chronic obstructive pulmonary disease, Clin. Exp. Allergy, vol. 41, no. 10, pp. 1371–1378, 2011.
  • [22] K. Kruczak, L. Mastalerz, and K. Sładek, “nterferon-gamma release assays and tuberculin skin testing for diagnosing latent Mycobacterium tuberculosis infection in at-risk groups in Poland, Int. J. Mycobacteriology, vol. 5, no. 1, pp. 27–33, Mar. 2016.
  • [23] N. M. Zetola et al., Diagnosis of pulmonary tuberculosis and assessment of treatment response through analyses of volatile compound patterns in exhaled breath samples, J. Infect., vol. 74, no. 4, pp. 367–376, Apr. 2017.
  • [24] P. Paredi, S. A. Kharitonov, and P. J. Barnes, Elevation of Exhaled Ethane Concentration in Asthma, Am. J. Respir. Crit. Care Med., vol. 162, no. 4, pp. 1450–1454, Oct. 2000.
  • [25] W. Cao and Y. Duan, Breath Analysis: Potential for Clinical Diagnosis and Exposure Assessment. Clin Chem, 52(5) (2006) 800-811
  • [26] T. Dymerski, J. Gębicki, P. Wiśniewska, M. Śliwińska, W. Wardencki, and J. Namieśnik, Application of the Electronic Nose Technique to Differentiation between Model Mixtures with COPD Markers, Sensors, vol. 13, no. 4, pp. 5008–5027, Apr. 2013.
  • [27] A. Riley, S. Krisher, and K. Mehta, Breath and Air Analysis: Applications in Resource-poor Settings, Procedia Eng., vol. 107, pp. 215–222, 2015.
  • [28] V. Ruzsanyi, J. I. Baumbach, S. Sielemann, P. Litterst, M. Westhoff, and L. Freitag, Detection of human metabolites using multi-capillary columns coupled to ion mobility spectrometers, J. Chromatogr. A, vol. 1084, pp. 145–151, 2005.
  • [29] F. Di Francesco, R. Fuoco, M. G. Trivella, and A. Ceccarini, Breath analysis: trends in techniques and clinical applications, 2004.
  • [30] A. C. Acta, S. Armenta, M. Alcala, and M. Blanco, A review of recent, unconventional applications of ion mobility spectrometry (IMS), Anal. Chim. Acta, vol. 703, pp. 114–123, 2011.
  • [31] A. Amann, G. Poupart, S. Telser, M. Ledochowski, A. Schmid, and S. Mechtcheriakov, Applications of breath gas analysis in medicine, Int. J. Mass Spectrom., vol. 239, pp. 227–233, 2004.
  • [32] H. J. Gordon, S.M., Szidon, J.P., Krotoszynski, B.K., Gibbons, R.D., O’Neill, Volatile organic compounds in exhaled air from patients with lung cancer, Clin. Chem., vol. 31, no. 8, pp. 1278–1282, 1985.
  • [33] G. Peng et al., Detection of lung, breast, colorectal, and prostate cancers from exhaled breath using a single array of nanosensors, Br. J. Cancer, vol. 103, no. 4, pp. 542–551, 2010.
  • [34] V. Ruzsányi et al., Is breath acetone a biomarker of diabetes? A historical review on breath acetone measurements, J. Breath Res. J. Breath Res, vol. 7, no. 7, pp. 37109–18, 2013.
  • [35] T. Do, C. Minh, D. R. Blake, and P. R. Galassetti, The clinical potential of exhaled breath analysis for diabetes mellitus, Diabetes Research and Clinical Practice, 97(2) (2012) 195-205
  • [36] B. Grabowska-Polanowska, M. Skowron, P. Miarka, A. Pietrzycka, and I. Śliwka, The application of chromatographic breath analysis in the search of volatile biomarkers of chronic kidney disease and coexisting type 2 diabetes mellitus, 2017.
  • [37] R. Fend, C. Bessant, A. J. Williams, and A. C. Woodman, Monitoring haemodialysis using electronic nose and chemometrics. Biosens. Bioelectron., vol. 19, no. 12, pp. 1581–90, Jul. 2004.
Document Type
article
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-50b7279f-c187-4050-8213-556a8c2edbab
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.