INFLUENCE OF PECTIN AND CHITOSAN ON THE PROPERTIES OF GELS PROTECTING THE OESOPHAGEAL MUCOSA

• Authors: Katarzyna Małolepsza-Jarmołowska
• Languages of publication: EN

Abstracts

EN

Among the diseases of the digestive tract, gastro-oesophageal reflux is one of the most troublesome ailments. It is estimated that in highly developed countries, reflux symptoms occur in about 5%-10% of people every day. It has also been found that about 20% of people experience such symptoms once a week. The incidence of this disease increases with age, regardless of gender. The aim of the study was to investigate the physicochemical properties of gels intended for the protection of the oesophageal mucosa. Preparations containing 3.0% pectin showed the lowest pH. These gels can be used in the treatment of advanced alkaline reflux. The addition of chitosan to all tested gels increased their pH and dynamic viscosity. The texture tests showed the effect of pectin concentration on the adhesion work of the tested gels.

Keywords

EN

anti-inflammatory drugs; gastro-oesophageal reflux; hydrophilic gels; oesophageal infections; oesophageal mucosa; physiological environment of gastro-oesophagus

• Publisher: Sieć Badawcza Łukasiewicz - Polskie Towarzystwo Chitynowe
• Journal: Progress on Chemistry and Application of Chitin and its Derivatives
• Year: 2021
• Volume: 26
• Pages: 162-169

Contributors

author

Katarzyna Małolepsza-Jarmołowska

• Department of Drugs Form Technology, Faculty of Pharmacy The “Silesian Piasts” memorial Wroclaw Medical University,

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• Document Type: article