Interstitial pneumonia during treatment with rituximab

• Authors: Dominika Leś , Anna Polakiewicz-Gilowska , Beata Kaleta , Danuta Starzyczny-Słota , Elżbieta Nowara
• Languages of publication: EN

Abstracts

EN

Rituximab (RTX) is a chimeric anti-CD20 antibody. It plays an important role in the treatment of B-cell lymphomas and diseases of autoaggression. RTX-induced lung disease is a rare entity, which should be considered in those patients treated with RTX who present with pulmonary disorders with no clear evidence of infection. A 37-year-old woman suffering from CD20-positive DLBCL (diffuse large B-cell lymphoma) received two cycles of the R-CHOP (RTX, cyclophosphamide, doxorubicin, vincristine and prednisone) regimen. After the second cycle of immunochemotherapy, symptoms of interstitial pneumonia occurred. Having excluded all the other causes, it was diagnosed as a complication associated with the administration of RTX.

Keywords

EN

complications   interstitial pneumonia   rituximab  

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Education
• Journal: OncoReview
• Year: 2015
• Volume: 5
• Issue: 1
• Pages: A16-A20

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• Document Type: article