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2018 | 103 | 1-18
Article title

Synthesis, spectral (FT-IR, 1H and 13C NMR) and antimicrobial studies some of (E)-2-(2-((aryl)(phenyl)methylene)hydrazinyl)benzo[d] thiazole

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Abstracts
EN
A series of (E)-2-(2-((aryl)(phenyl)methylene)hydrazinyl)benzo[d] thiazole compounds by condensation of substituted benzophenone with 2-hydrazinobenzothizol in the presence acetic acid. The synthesized compounds 1-6 were characterized by elemental, FT-IR, 1H and 13C NMR spectral data. From the IR and NMR spectra, the characteristic frequencies were assigned and the data used for confirmation of the formation hydrazones 1-6. All compounds were screened for their preliminary antibacterial and antifungal activities. The methoxy substituted compound 6 shows good antibacterial activity against their bacterial strains within the agreed mm of zone of inhibition. The methyl (5) and methoxy (6) substituted hydrazones show good antifungal activities against their fungal strains.
Year
Volume
103
Pages
1-18
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author
  • Department of Chemistry, Annamalai University, Annamalainagar - 608002, India
  • Department of Chemistry, Annamalai University, Annamalainagar - 608002, India
References
  • [1] G. Uppal, S. Bala , S. Kamboj, M. Saini, Der Pharma Chem. 3 (2011) 250.
  • [2] Delgado, J. N.; Remers, W. A. In Textbook of Organic Chemistry Medicinal and Pharmaceutical Chemistry; Wilson, Giswold’s; Lippincott Raven: Philadelphia, 1998.
  • [3] Jha, K. K.; Kumar, S.; Tomer, I.; Mishra, R. J. Pharm Res 2012, 5, 560.
  • [4] G. Stefancich, R. Silvestri, A. Retico, M. Artico, G. Simonetti, Arch. Pharmzie 325 (1992) 199.
  • [5] M. M. H. Bhuiyan, K.M.M. Rahman, M.K. Hossain, A. Rahim, M.I. Hossain, M. Abu Naser, Acta Pharm. 56 (2006) 441.
  • [6] Fujii, K.; Tsutsumiuchi, K.; Yamanaka,Y.; Nakamura, K. Jpn. Pat. 1999, 11116555; Chem. Abstr. 130, 325151w.
  • [7] H.Z. Zhang, S. Kasibhatla, J. Kuemmerle, W. Kemnitzer, K. Ollis-Mason, L. Qiu, C. Crogan-Grundy, B. Tseng, J. Drewe, S. X. Cai, J. Med. Chem. 48 (2005) 5215.
  • [8] S.A. El-Feky, Z.K. Abdel-Samii, Pharmazie 50 (1995) 341.
  • [9] G.D. Nanteuil, Y. Herve, J. Duault, J. Espeinal, M. Boulanger, D. Ravel, Arzneim Forsch Drug Res. 45 (1995) 1175.
  • [10] M. Palaci, R. Dietze, D. J. Hadad, Journal of Clinical Microbiology 45 (2007) 4064.
  • [11] F. Drobniewski, Y. Balabanova, M. Ruddy, Infectious Diseases 8 (2002) 1320.
  • [12] M. E. Kimerling, P. Phillips, P. Patterson, M. Hall, C. A. Robinson, N. E. Dunlap, Chest. 113 (1998) 1178.
  • [13] E. Mokaddas, S. Ahmad, A.T. Abal, A.S. Al-Shami, Annals of Saudi Medicine 25 (2005) 150.
  • [14] M.H. Habibi, A. Hassanzadeh, A.Z. Isfahani, Dyes and Pigments 69 (2006) 93.
  • [15] A. Zagade, G. P. Senthilkumar, Der Pharm Chemica 3 (2011) 523.
  • [16] T. Aoyama, S. Murata, I. Arai, N. Araki, T. Takido, Y. Suzuki, M. Kodomari, Tetrahedron 62 (2006) 3201.
  • [17] M. Kachroo, G. K. Rao, S. Rajasekaran, S. P. N. Pai, Y. R. Hemalatha, Der Pharm Chemica 3 (2011) 241.
  • [18] S. J. Kashyap, P. K. Sharma, V. K. Garg, R. Dudhe, N. Kumar, J. Adv Sci Res 2 (2011) 18.
  • [19] O. Kouatly, A. Geronikaki, C. Kamoutsis, D. HadjipavlouLitina, P. Eleftheriou, Eur J Med Chem. 44 (2009) 1198.
  • [20] R. S. Koti, G. D. Kolavi, V. S. Hegde, I. M. Khaji, Indian J Chem 45B (2006) 1900.
  • [21] K. Singh, G. Mishra, K. Jyoti, J. App Pharm Sci. 1 (2011) 44.
  • [22] D. Willner, P.A. Trail, S.J. Hofstead, H.D. King, S.J. Lasch, G.R. Braslawsky, R.S. Greenfield, T. Kaneko, R.A. Firestone, Bioconjug. Chem. 4 (1993) 521.
  • [23] F. Kratz, U. Beyer, T. Roth, N. Tarasova, P. Collery, F. Lechenault, A. Cazabat, P. Schumacher, C. Unger, U. Falken, J. Pharm. Sci. 87 (1998) 338.
  • [24] G. Di Stefano, L. Fiume, M. Domenicali, C. Busi, P. Chieco, F. Kratz, M. Lanza, A. Mattioli, M. Pariali, M. Bernardi, Digest. Liver Dis. 38 (2006) 404.
  • [25] W. B. Hugo, P. D. Russell, Pharmaceutical Microbiology, Blackwell Scientific Publication: Oxford; 4, 1987, 265.
  • [26] F. J. Baker, R. M. Breach, Medical Microbiology Techniques, London Butterworths: London, 1990, 422.
  • [27] H. Nakahara, T. Ishikawa, Y. Sarai, T. Konda, S. Mitsuhashi, Nature, 266, 1977, 165.
  • [28] G. James, N. Sherman, Microbiology, A Laboratory Manual, The Benjamin Publishing Company, California, 3, 1992, 77.
  • [29] R. Murray, E. J. Baron, M. A. Pfaller, F. C. Tenover, R. H. Yolke, Manual of Cilinical Biology, ASM, Washington DC, 1995, 6.
  • [30] N.P.G. Roeges, A Guide to the Complete Interpretation of Infrared Spectra of Organic Structure, Wiley, New York., 1994.
  • [31] Jag mohan, Organic Spectroscopy, Narosa publishing house, New Delhi, 2004
  • [32] R. Arulkumaran, V. Manikandan, G. Thirunarayanan, World Scientific News 80 (2017) 239.
  • [33] G. Thirunarayanan, I. Muthuvel, V. Sathiyendiran, Int. Lett. Chem. Phys. Astro. 48 (2015) 114.
  • [34] R.M. Silverstein, F.X. Webster, Spectroscopic Identification of Organic Compounds, seventh ed., wiley, New York., 2005.
  • [35] D.L. Vein, N.B. Colthup, W.G. Fateley, J.G. Grasselli, The handbook of infrared and Raman characteristic frequencies of organic molecules, Academic press, New York., 1991.
  • [36] A.W. Bauer, W.M.M. Kirby, J. C. Sherris and M. Truck, Americal Journal of Clinical Pathology 45 (1966) 493.
Document Type
article
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-41b600f2-5387-4330-b932-9d4c3bc31c2b
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