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Journal
2015 | 5 | 2 | A53-56
Article title

Effective treatment of severe hypertensive crisis in 2-year-old child with neuroblastoma

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EN
Abstracts
EN
We describe a case of a 2-year-old boy with neuroblastoma and high catecholamine levels which developed a severe hypertensive crisis. An oral propranolol and oral angiotensin-converting enzyme inhibitor were used with a mild short transient benefit. However, an intravenous labetalol and oral doxazosin used for over 3 weeks resulted in successful blood pressure control. This report highlights the prolonged use of α and β-adrenergic antagonist therapy in children with neuroblastoma with refractory catecholamine-induced hypertension.
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Journal
Year
Volume
5
Issue
2
Pages
A53-56
Physical description
Contributors
  • Department of Surgical Oncology for Children and Y outh, Institute of Mother and Child, Warsaw, Poland, anna.raciborska@hoga.pl
  • Department of Surgical Oncology for Children and Y outh, Institute of Mother and Child, Warsaw, Poland
  • Department of Nephrology, Kidney Transplantation and Hypertension, The Children’s Memorial Health Institute, Warsaw, Poland
  • Department of Surgical Oncology for Children and Y outh, Institute of Mother and Child, Warsaw, Poland
  • Pediatric Oncology, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center , Harvard Medical School, Boston , USA
  • Department of Cardiology, Institute of Mother and Child, Warsaw, Poland
References
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  • Thomas CA. Drug treatment of hypertensive crisis in children. Paediatr Drugs 2011; 13(5): 281-290.
  • Hernandez MR, Shamberger RC, Seefelder C. Catecholamine-secreting neuroblastoma in a 4-month-old infant: perioperative management. J Clin Anesth 2009; 21(1): 54-56.
  • Pappas L, Shamberger RC, Seefelder C. Giant, dopamine secreting thoracoabdominal neuroblastoma in a 2-year-old: rapid preoperative blockade with labetalol. J Pediatr Hematol Oncol 2010; 32(2): 163-166.
  • Thomas CA, Moffett BS, Wagner JL et al. Safety and efficacy of intravenous labetalol for hypertensive crisis in infants and small children. Pediatr Crit Care Med 2011; 12(1): 28-32.
  • Mazza A, Armigliato M, Marzola MC et al. Anti-hypertensive treatment in pheochromocytoma and paraganglioma: current management and therapeutic features. Endocrine 2014; 45(3): 469-478.
  • Park SH, Lee YS, Min TJ et al. Anesthetic management of hypertensive crisis in a three-year-old patient with undiagnosed severe renal artery stenosis: a case report. Korean J Anesthesiol. 2014; 67(4): 275-278.
Document Type
article
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YADDA identifier
bwmeta1.element.psjd-3f8d01d5-3056-4f6a-86b4-671c9b2cd7b0
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