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2015 | 5 | 2 | A53-56
Article title

Effective treatment of severe hypertensive crisis in 2-year-old child with neuroblastoma

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We describe a case of a 2-year-old boy with neuroblastoma and high catecholamine levels which developed a severe hypertensive crisis. An oral propranolol and oral angiotensin-converting enzyme inhibitor were used with a mild short transient benefit. However, an intravenous labetalol and oral doxazosin used for over 3 weeks resulted in successful blood pressure control. This report highlights the prolonged use of α and β-adrenergic antagonist therapy in children with neuroblastoma with refractory catecholamine-induced hypertension.
Physical description
  • Department of Surgical Oncology for Children and Y outh, Institute of Mother and Child, Warsaw, Poland
  • Department of Surgical Oncology for Children and Y outh, Institute of Mother and Child, Warsaw, Poland
  • Department of Nephrology, Kidney Transplantation and Hypertension, The Children’s Memorial Health Institute, Warsaw, Poland
  • Department of Surgical Oncology for Children and Y outh, Institute of Mother and Child, Warsaw, Poland
  • Pediatric Oncology, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center , Harvard Medical School, Boston , USA
  • Department of Cardiology, Institute of Mother and Child, Warsaw, Poland
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