Elektroretinogram stymulowany wzorcem oraz fotopowa negatywna odpowiedź w diagnostyce jaskry

Lubiński, Wojciech; Kirkiewicz, Marta; Karaśkiewicz, Joanna

Journal

OphthaTherapy

2017 | 4 | 2 | 73-80

Article title

Elektroretinogram stymulowany wzorcem oraz fotopowa negatywna odpowiedź w diagnostyce jaskry

Authors

Wojciech Lubiński , Marta Kirkiewicz , Joanna Karaśkiewicz

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OPT_2-2017_Elektroretinogram stymulowany wzorcem_w.pdf

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Pattern electroretinography and photopic negative response in glaucoma diagnostics

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Abstracts

Celem niniejszego artykułu jest przedstawienie danych z najnowszej literatury i doświadczeń własnych dotyczących roli elektroretinogramu stymulowanego wzorcem (PERG) oraz fotopowej negatywnej odpowiedzi (PhNR) w diagnostyce jaskry. Wyniki tych badań wykazują, że redukcja amplitudy PERG jest wskaźnikiem konwersji do pełnoobjawowej jaskry i przyspieszonej progresji ścieńczenia włókien nerwowych siatkówki u pacjentów z podejrzeniem jaskry. Za pomocą PERG i PhNR można wykryć zaburzenia funkcji siatkówki w jaskrze w momencie, gdy wyniki rutynowych badań diagnostycznych są niemiarodajne bądź mieszczą się w granicach normy. PERG i PhNR stanowią dowód na odwracalność dysfunkcji komórek zwojowych siatkówki. Badania te mogą służyć także jako wskaźnik dobrze dobranego leczenia obniżającego ciśnienie wewnątrzgałkowe (CWG). Przy podejrzeniu jaskry normociśnieniowej PERG może być jedynym wskaźnikiem zaburzenia funkcji komórek zwojowych siatkówki i stanowić podstawę włączenia leczenia obniżającego CWG.

The aim of this article is to present data from recent literature and our own experience with respect to the role of pattern electroretinography (PERG) and photopic negative response (PhNR) in glaucoma diagnosis. The results of these studies show that PERG amplitude reduction is an indicator of conversion to manifest glaucoma and a predictor of increased rate of progression of retinal nerve fiber layer (RNFL) thinning in patients with glaucoma suspicion. PERG and PhNR are capable of detecting decreased retinal function when the results of routine diagnostic examinations are still within normal ranges or borderline. PERG and PhNR may also serve to confirm retinal function improvement. Both tests may also serve as an indicator of well-selected IOP-lowering therapy. In patients suspected of normal-tension glaucoma, PERG may be the only indicator of RGCs dysfunction and may be the diagnostic basis for the inclusion of IOP-lowering therapy.

Keywords

diagnostyka jaskry elektroretinogram stymulowany wzorcem fotopowa negatywna odpowiedź

Discipline

MEDICINE: MEDICINE

Publisher

Medical Education

Journal

OphthaTherapy

Year

2017

Volume

Issue

Pages

73-80

Physical description

Contributors

author

Wojciech Lubiński

Klinika i Katedra Okulistyki, Pomorski Uniwersytet Medyczny w Szczecinie

author

Marta Kirkiewicz

martakiszkielis@gmail.com

Klinika i Katedra Okulistyki, Pomorski Uniwersytet Medyczny w Szczecinie

author

Joanna Karaśkiewicz

Klinika i Katedra Okulistyki, Pomorski Uniwersytet Medyczny w Szczecinie

References

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article

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