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2018 | 107 | 185-195
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Synthetic chromosome - the first element for synthetic life

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Synthetic biology is a scientific area, that link together domains such as: biotechnology, microbiology, system biology, genetic engineering and bioinformatics. The main goal of synthetic biology is to constructing and designing artificial biological systems or re-design of existing biological systems for useful purposes - synthesizing for knowledge and synthesizing for products. The main structure on which synthetic biologists focus is the chromosome. Thanks to the development of modern genome editing techniques such as CRISPR/Cas9, or DNA assembly methods in recent years, there are more and more possibilities of creating synthetic chromosomes. The current achievements give hope for the construction of a fully synthetic organism into the future, as well as open up new possibilities related to the synthesis of new products. The following paper presents actual knowledge about synthetic chromosome including the topic of genome editing method and potential applications of synthetic biology.
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  • Faculty of Biological Sciences, University of Wroclaw, 35 Kuźnicza Str., 50-138 Wroclaw, Poland
  • Faculty of Biological Sciences, University of Wroclaw, 35 Kuźnicza Str., 50-138 Wroclaw, Poland
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