CD30-positive T-cell lymphoproliferation of the bulbar conjuntival mucosa showing spontaneous remission

• Authors: Marticorena Álvarez Paula , Guadalupe Garrido Ceca , Mercedes Guijarro Rojas
• Languages of publication: EN

Abstracts

EN

Introduction: CD30-positive T-cell lymphoproliferative lesions represent a spectrum of heterogeneous disorders. Clinical case: An incision biopsy was performed in a 25-year-old man with a lump in the bulbar conjunctiva. Immunohistochemistry indicated membrane positivity for CD3 and CD30 in over 75%. PCR identified the monoclonal nature of the T-cells. The hematological study was normal. Following biopsy, the conjunctival tumor diminished until disappear. Conclusions: Mucosal CD30-positive T-cell lymphoproliferation could be ascribed to a reactive process but it is necessary to rule out a primary conjunctival tumor or the first manifestation of an anaplastic large cell lymphoma.

Keywords

EN

CD30; T-cell; conjunctival; lymphoproliferative

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Education
• Journal: OphthaTherapy
• Year: 2021
• Volume: 8
• Issue: 1
• Pages: 45-48

Contributors

author

Marticorena Álvarez Paula

• Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain

author

Guadalupe Garrido Ceca

• Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain

author

Mercedes Guijarro Rojas

• Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain

References

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• 2. Sciallis AP, Law ME, Inwards DJ et al. Mucosal CD30-positive T-cell lymphoproliferative of the head and neck show a clinicopathologic spectrum similar to cutaneous CD30-positive T-cell lymphoproliferative disorders. Mod Pathol. 2012; 25(7): 983-92.
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• 5. Liu F, Li M, Zhang LY et al. Clinicopathologic features of primary mucosal CD30-positive T-cell lymphoproliferative disorders in head and neck region. Zhonghua Bing Li Xue Za Zhi. 2018; 47(6): 412-6.

• Document Type: article