Potencjalne znaczenie diagnostyczne lipokaliny neutrofilowej związanej z żelatynazą

• Authors: Aleksandra Radosz , Anna Obuchowicz

Title variants

EN

Potential diagnostic significance of neutrophil gelatinase-associated lipocalin

• Languages of publication: PL

Abstracts

PL

Rola lipokaliny neutrofilowej związanej z żelatynazą (neutrophil gelatinase-associated lipocalin – NGAL) stanowi przedmiot badań w wielu dziedzinach medycyny. Jest to białko zewnątrzkomórkowe wydzielane przez komórki przewodu pokarmowego, układu oddechowego, komórki cewek nerkowych oraz układu immunologicznego. Bierze udział w ostrych i przewlekłych procesach zapalnych oraz onkogenezie. Zyskało w nefrologii pozycję kandydata na „nowy” marker uszkodzenia nerek. Na podstawie doniesień naukowych z innych dziedzin, jak: chirurgia, onkologia czy diabetologia można stwierdzić, że przydatność diagnostyczna, a także rokownicza tego białka może potencjalnie obejmować wiele jednostek chorobowych.

EN

Neutrophil gelatinase-associated lipocalin (NGAL) has been the subject of studies in various medical fields. It belongs to extracellular proteins, is secreted by such cells as respiratory and intestinal epithelial cells, cells of the immune system and tubuli cells in the kidneys. NGAL is engaged in acute and chronic inflammatory processes and oncogenesis. It is a candidate to become the new marker of kidney injury, however, based on numerous studies in different medical areas like surgery, oncology or diabetology the diagnostic and also prognostic significance of NGAL may include more than only kidney disorders.

Keywords

EN

adults; children; diagnostic significance; dorośli; dzieci; lipokalina neutrofilowa związana z żelatynazą; neutrophil gelatinase-associated lipocalin; przydatność diagnostyczna

Discipline

• MEDICINE: MEDICINE

• Publisher: Śląski Uniwersytet Medyczny w Katowicach
• Journal: Annales Academiae Medicae Silesiensis
• Year: 2013
• Volume: 67
• Issue: 1
• Pages: 61–66

Contributors

author

Aleksandra Radosz

• Katedra i Oddział Kliniczny Pediatrii Wydziału Nauk o Zdrowiu Śląskiego Uniwersytetu Medycznego w Katowicach

author

Anna Obuchowicz

• Katedra i Oddział Kliniczny Pediatrii Wydziału Nauk o Zdrowiu Śląskiego Uniwersytetu Medycznego w Katowicach ul. Batorego 15 41-902 Bytom tel. [phone]

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• Document Type: article