The global economy and, more precisely, the participation in it is the objective itself which most enterprises would like to achieve. Unfortunately, the requirements that need to be fulfilled in order to participate in it are very often insurmountable barriers for large enterprises of the national economy, being at the medium and low level of the economic growth. Therefore, it is important for the country to know its leading industries to make every effort to strengthen them. The local economy is a valuable source of information on the location of industries which constitute the whole of specializations of the country. The paper makes uses of clusters as an output variable for the assessment of the industrial direction of the region. The research process refers to verifying the selected economic factors and comparing them to the possibilities of clusters in order to determine the specialization of the region.