Bacteriuria of women of child bearing age
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Urinary tract infection (UTI) is one of the most common diseases encountered worldwide. In this study, urine samples were collected from thirty women of child bearing age (18-25 years) to determine the prevalence of bacteriuria, as well as the presence of pus cells and white blood cells which are signs of infection. The urine microscopy result revealed that 7 (23.3%) of the sample had greater than 10 leucocytes per high power field. Only four of the samples had a significant number of pus cells. The bacteria count recorded ranged from 25 cfu/0.001 ml to 276 cfu/0.001 ml. Of the samples, 13 were positive for bacteriuria having bacterial count greater than 100 cfu/0.001 ml. The bacteria isolates include Klebsiella spp. (3.8%), Streptococcus spp. (2.5%). Escherichia coli (62.5%) and Staphylococcus spp. (21.2%). Of these, Klebsiella spp. was the least prevalent and Escherichia coli had the highest number of occurrence. These organisms were very sensitive to Ciprofloxacin, Pefloxacin, Zinnacef and Gentamycin according to the antimicrobial susceptibility test carried out. Ciprofloxacin was found to be the most effective antibiotics against all the bacterial isolates. Here, zones of inhibition ranged from 15 mm (Streptococcus spp.) to 20 mm (Escherichia coli). All the bacterial isolates were resistant to Amoxicillin, with zones of inhibition between 11 (Klebsiella spp., Escherichia coli, Staphylococcus spp.) and 13 mm (Streptococcus spp.). Since the prevalence of asymptomatic bacteriuria is high, early diagnosis and proper treatment is necessary in order to prevent it from becoming symptomatic.
-  A. W. Asscher, S. Chick, N. Radford. Natural history of asymptomatic bacteriuria in non-pregnant women. In: Brumfit W., Asscher AW., Editors. Urinary tract infection. London: Oxford University Press (2000) 51-60.
-  G. I. Barrow, G.I. & R. K.A. Feltham. Cowen and Steel Manual for the Identification of Medical Bacteria.3rd edition. Cambridge University Press 1994.
-  Chaudhry, W. J. Stone, J. A. Breyer. Occurrence of pyuria and bacteriuria in asymptomatic hemodialysis patients. American Journal of Kidney Diseases 21 (1995) 180-3; 27 (2000) 91-5.
-  R. Colgan, L. E. Nicolle, A. McGlone, T. M. Hooton. Asymptomatic bacteriuria in adults. Am Fam Physician 14 (6) (2006) 985-90.
-  F. G. Cunningham, N. F. Grant, K. J. Leveno, L. C. Gilstrap, J. C. Hauth, K. D. Wenstrom. Renal and Urinary tract disorders In: Williams Obstetrics (Gunningham F.G., Gant N.F et al. eds) 21st Edn. Mc Graw-Hill, Medical Publishing Division New York (2001) 1251-1271.
-  Garingalo-Molina, F.D. Asymptomatic bacteriuria among pregnant women: Overview of Diagnostic Approaches. Phil J Microbiol Infect Dis 29 (2000) 197-186.
-  Kass, E.H. Bacteriuria and the diagnosis of infections of the urinary tract. Archive of International Medicine 2 (1957) 100: 709-14.
-  Kass, E.H. Asymptomatic infections of the urinary tract. 1956. In: J Urol. 167 (2002). 2(2): 1016-9; discussion 1019-21.
-  Miller, L.K. and Cox, S.M. Urinary tract infection complicating pregnancy. Infect Dis Clin of North Am 11 (1997) 13-26.
-  Nicolle, L.E. Asymptomatic bacteriuria: when to screen and when to treat. Infectious Disease of Clinical North America 17 (2) (2003) 94-367.
-  Nicolle, L.E. Asymptomatic bacteriuria in the elderly. Infectious Diseases of Clinical North America 11 (2005) 647-62.
-  L. E. Nicolle, S. Bradley, R. Colgan, J. C. Rice, A. Schaeffer, T. M Hooton. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clinical Infectious Diseases 40 (2005) 643-54.
-  Nicolle, L.E. Urinary antibody level and survival in bacteriuric institutionalized elderly subjects. Journal of American Geriatrics Society 46 (2006) 947-53.
-  Nicolle, L.E. Asymptomatic bacteriuria: review and discussion of the IDSA guidelines. International Journal of Antimicrobial Agents 1 (2006) 12-8.
-  T. F. Patterson & V. T. Andriole. Bacteriuria in pregnancy. Current treatment options in infectious disease 5 (2003) 81-87.
-  R. H. Rubin, E. D. Shapiro, V. T. Andriole, R. J. Davis, W. E. Stamm. Evaluation of new anti-infective drugs for the treatment of urinary tract infection. Clinical Infectious Diseases 15(1) (2008) 216-27.
-  Smaill, F. Antibiotics for asymptomatic bacteriuria in pregnancy (Cochrane Review). In the Reproductive Health Library, Issue 9, Oxford: Update Software Ltd. 2006.
-  G. G. Zhanel, G. K. Harding, L. E. Nicolle. Asymptomatic bacteriuria in patients with diabetes mellitus. Review of Infectious Diseases 13 (2007) 150-4.
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