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2018 | 105 | 212-217
Article title

Head transplant - the newest reports and concerns on planned procedure

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EN
Abstracts
EN
Transplantation, one of the most intensively developing fields of medicine, is giving patients hope for the chance of "second life" and health. The 21st century medical achievements heralded to achieve more difficult challenges, such as face transplant or lower extremity transplant. Among the futuristic dreams of the scientists, one of the projects - the Head to Body Transplant, stands out as one of the most controversial surgeries of the century. The aim of this study was to present the current state of art in medical aspect on cephalic anastomosis, as well as ethical implications. Among articles in PubMed Medline database related to human cephalic anastomosis, head transplant, head to body transplant keywords, 15 articles were selected for further analysis. Reviewed research presents significant development in conduction of the human cephalic anastomosis project. Most of the crucial parts of the surgery, such as deep profound hypothermia, spinal cord anastomosis - the detachment and fusion with the fusiogenes particles, have been practiced on animal models. The more newest revelations are revealed to the public, the more ethical and technical concerns are raised, primarily in terms of one-center study aprroach, infavourable benefit-cost ratio and futuristic apprehensions of infertility, transsexual or even unnatural life prolongation reasons for performing this type of surgery.
Discipline
Year
Volume
105
Pages
212-217
Physical description
Contributors
  • I Faculty of Medicine, Medical University of Lublin, Al. Raclawickie 1, 20-059 Lublin, Poland
  • Pediatric Neurology Department, III Chair of Pediatrics, Medical University of Lublin, 6 Prof. A. Gebali Str., 20-093 Lublin, Poland
References
  • [1] Bock J. The jubilee of the first successful optic keratoplasty by Eduard Zim. Wien Klin Wochenschr. (1958) May 23; 70(21): 381-3.
  • [2] Tröhler U. Emil Theodor Kocher (1841-1917). J R Soc Med. (2014) Sep; 107(9): 376-7.
  • [3] Theodorakopoulou E, Meghji S, Pafitanis G, Mason KA. A review of the world's published face transplant cases: ethical perspectives. Scars Burn Heal. (2017) Mar 21; 3: 2059513117694402.
  • [4] Cavadas PC, Thione A, Carballeira A, Blanes M. Bilateral transfemoral lower extremity transplantation: result at 1 year. Am J Transplant. (2013) May; 13(5): 1343-9.
  • [5] Aida L. Alexis Carrel (1873-1944): visionary vascular surgeon and pioneer in organ transplantation. J Med Biogr. (2014) Aug; 22(3): 172-5.
  • [6] Lamba N, Holsgrove D, Broekman ML. The history of head transplantation: a review. Acta Neurochir (2016) 158: 2239–2247.
  • [7] White RJ, Wolin LR, Massopust LC, Taslitz N, Verdura J Cephalic exchange transplantation in the monkey. Surgery (1971) 70(1): 135–139
  • [8] Li PW, Zhao X, Zhao YL, Wang BJ, Song Y, Shen ZL et al. A cross-circulated bicephalic model of head transplantation. Surg Neurol Int. (2016) 7(Suppl 24): S623–S625
  • [9] Ren XP, Canavero S. Human head transplantation. Where do we stand and a call to arms. Surg Neurol Int. (2016) 7: 11.
  • [10] Canavero S. HEAVEN: The head anastomosis venture project outline for the first human head transplantation with spinal linkage (GEMINI) Surg Neurol Int. (2013) 4 (Suppl 1): S335–S342.
  • [11] Canavero S, Ren X, Kim C-Y, Rosati E. Neurologic foundations of spinal cord fusion (GEMINI). Surgery (2016) 160(1): 11–19
  • [12] Ye Y, Kim CY, Miao Q, Ren X. Fusogen-assisted rapid reconstitution of anatomophysiologic continuity of the transected spinal cord. Surgery (2016) Jul; 160(1): 20-25.
  • [13] Cho Y, Borgens RB. Polymer and nano-technology applications for repair and reconstruction of the central nervous system. Exp Neurol. (2012) 233: 126–44.
  • [14] Borgens RB. Cellular engineering: Molecular repair of membranes to rescue cells of the damaged nervous system. Neurosurgery. (2001) 49: 370–8
  • [15] Canavero S. Ren XP. Houston, GEMINI has landed: Spinal cord fusion achieved. Surg Neurol Int. (2016) 7(Suppl 24): S626–S628.
  • [16] Ren X, Li M, Zhao C, Liu Z, Ren S et al. First cephalosomatic anastomosis in a human model. Surg Neurol Int. (2017) Nov 17; 8:276.
  • [17] Cuoco JA. Reproductive implications of human head transplantation. Surg Neurol Int. (2016) 7: 48.
  • [18] Čartolovni A, Spagnolo AG. Ethical considerations regarding head transplantation. Surg Neurol Int. (2015) 6: 103.
  • [19] Canavero S, Ren XP, Kim CY. HEAVEN: The Frankenstein effect. Surg Neurol Int. (2016) Sep 13; 7 (Suppl 24): S623-5.
  • [20] Brennum J, Ethico-legal Committee of the European Association of Neurosurgical Societies (EANS). The EANS Ethico-legal Committee finds the proposed head transplant project unethical. Acta Neurochir (Wien). (2016) Dec; 158(12): 2251-2252.
  • [21] Paul NW, Caplan A, Shapiro ME, Els C, Allison KC et al. Human rights violations in organ procurement practice in China. BMC Med Ethics (2017) 18: 11
Document Type
short_communication
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-2c9a788b-df30-44cc-ab03-42ab11e92744
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