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2020 | 30 | 2 | 89-95
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Investigation on the Role of Nanoparticle on Microbial Nano Interface to Understand Pathogenecity

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Nano-biotechnology represents the intersection of nanotechnology and biotechnology which is an emerging field in creation, productivity and utility of nanoscale structures for advanced biotechnology. Plant and plant extract are considered as green and effective paths in the synthesis of gold and silver nanoparticles. The aim of the present study is to analyze the interaction of silver nanoparticles synthesized from herbal source (Cinnamon zeylanicum) with pathogenic bacteria Salmonella typhi (S. typhi) in order to know the microbe pathogenicity. The micro-nano interface disturbed the growth of microbes. Under the influence of different concentration of nanoparticles (50 µL to 1,000 µL), the microbes exhibited slow growth as compared to control. The viable cell count also decreased as the nanoparticles concentration increased. This shows major difference in the bacterial culture of with and without nano particle. Under normal culture, without nanoparticles intervention, the microbes show lag phase at 0-4 h, the log phase begins and its exponential growth occurs between 4-8 h and after 12 h, stationary phase was attained. There was a slow growth observed when the culture was exposed to silver nanoparticles. This clearly shows the antimicrobial effect of nanoparticles. In this study we used green synthesized nanoparticles, which have shown a good antibacterial efficacy against the pathogenic microorganism Salmonella typhi.
Physical description
  • Nanobiotherapeutics Laboratory, National Centre for Nanoscience and Nanotechnology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India
  • Nanobiotherapeutics Laboratory, National Centre for Nanoscience and Nanotechnology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India
  • Nanobiotherapeutics Laboratory, National Centre for Nanoscience and Nanotechnology, University of Madras, Guindy Campus, Chennai 600025, Tamil Nadu, India
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