The evidence of Cross River State in Nigeria as a global visual cultural, biodiversity and wildlife tourism distinction located in West Africa is presented using photo-inventory. A socio-scientific photo-sourcing and explanation was carried out. The ancient city of Calabar that received early Christian missionaries to Nigeria is the capital of Cross River State in Nigeria, West Africa now host the Africa’s annual biggest street party (Calabar carnival). The ancient house of Mary Mitchell Slessor a Scottish missionary to Nigeria who stopped the ancient practice of killing of twins and multiple births built in 1848, stands in Calabar as a monument that attracts tourists from all parts of the world. The international Ekpe masquerade, boat and canoe race in Calabar, lebuko new yam festival in Ugep, Central Cross River are tourists attracted festivals. Being home of tropical forest with rare biodiversity added with wildlife, some mammals as endangered Gorilla, drill, chimpanzee and African black elephants, including different species of African Primates are seen in the protected zones of the National Park and Afi Wildlife Sanctuary. Photos of numerous huge ancient carved and engraved standing stones (Monoliths) dating back to 1200 BC are found in about 30 communities in Ikom, the Central part of Cross River State of Nigeria. Spectacular natural waterfalls for relaxation are in existence. The Obudu mountain Resort city exhibit the four weather type witness in Europe and America. The Resort is located on a mountain 1600 m high in the Northern Cross River State. Photos of the winding road from the bottom of the mountain to the top and nature dug swimming pools are places to visit.