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2013 | 18 | 18 | 77-83
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Aim of the study was to compare the effect of different molecular weight chitosan on activity of
peritoneal cells of mice during immunosupression caused by adult stages of Heligmosomoides
polygyrus. We observed that intraperitoneal injections of chitosan induce cell infiltration, but the
activity of recruited cells differed depending on the type of polysaccharide used. Low molecular
weight chitosan activated cells with inflammatory characteristics, while high molecular weight
polysaccharide reduced cell responsiveness to stimulation. Although IgA titers in the peritoneal
fluid were elevated, chitosan treatments had no effect on the level of infection.
Physical description
  • Faculty of Biology, University of Warsaw
  • Faculty of Biology, University of Warsaw
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