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2017 | 15 | 3 | 189–193
Article title

Frequency and pattern of gynecologic cancers from 2010 to 2014 in Beira, Mozambique

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Częstość występowania i profil nowotworów kobiecych narządów płciowych w latach 2010–2014 w mieście Beira w Mozambiku
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Objective: Gynecologic cancers represent a large health, social and economic burden worldwide. In low-income countries, particularly in Mozambique, little data is available and no effective policies are implemented to fight these diseases. Our objective was to trace the epidemiological profile of gynecologic cancers from 2010 to 2014 in Beira, Mozambique. Methods: We retrospectively reviewed the registers of the Department of Pathology of Central Hospital of Beira to identify all cases of gynecologic malignancies recorded from January 2010 to December 2014. Results: Most of the diagnosed female cancers (43.4%) were gynecologic and, among these, cervical cancer was definitely the most commonly reported cancer every year, ranging from 86.7% in 2013 to 93.3% in 2014. Conclusion: As in many low-income countries, the access to screening programs for gynecologic cancer is not effective in Mozambique; therefore urgent preventive policies are crucial to address this emergent issue.
Cel: Nowotwory kobiecych narządów płciowych stanowią istotne obciążenie zdrowotne, społeczne i ekonomiczne na całym świecie. W krajach o niskich dochodach, w szczególności w Mozambiku, brak jest zarówno dostępnych danych, jak i skutecznych strategii walki z tymi chorobami. Celem badania było prześledzenie profilu epidemiologicznego nowotworów ginekologicznych w latach 2010–2014 w mieście Beira w Mozambiku. Metoda: Autorzy dokonali retrospektywnego przeglądu rejestrów medycznych Oddziału Patologii Szpitala Centralnego w Beirze w celu wyodrębnienia wszystkich przypadków nowotworów kobiecych narządów płciowych odnotowanych w okresie od stycznia 2010 do grudnia 2014 roku. Wyniki: W większości przypadków (43,4%) rozpoznane u kobiet nowotwory dotyczyły narządów rodnych, przy czym rak szyjki macicy był zdecydowanie najczęściej odnotowywanym nowotworem w  każdym roku (od 86,7% w  2013 do 93,3% w 2014 roku). Wniosek: Podobnie jak w wielu krajach o niskich dochodach, również w Mozambiku dostęp do programów przesiewowych nowotworów narządów rodnych jest ograniczony – niezbędne jest pilne podjęcie działań prewencyjnych.
Physical description
  • Serviço de Anatomia Patológica, Hospital Central da Beira, Beira, Mozambique; Universidade Católica de Moçambique, Beira, Mozambique
  • Operational Research Unit, Doctors with Africa, Beira, Mozambique
  • Clinic of Infectious Diseases, University of Bari, Bari, Italy
  • Operational Research Unit, Doctors with Africa, Padua, Italy
  • Zerouno Procreazione, Centro di Medicina, Venezia Mestre (VE), Italy
  • Operational Research Unit, Doctors with Africa, Beira, Mozambique
  • 1. GLOBOCAN 2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. Available from: http://globocan. [cited: July 2016].
  • 2. Parkin DM, Bray F, Ferlay J et al.: Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74–108.
  • 3. US Centers for Disease Control and Prevention, 2006/2007 National Breast and Cervical Cancer Early Detection Program fact sheet. 2006.
  • 4. American Cancer Society: Cancer Facts & Figures 2015. Available from: [cited: July 2016].
  • 5. Chhabra S, Bhavani M, Deshpande A: Trends of vulvar cancer. J Obstet Gynaecol 2014; 34: 165–168.
  • 6. Wagner M, Bennetts L, Patel H et al.: Global availability of data on HPV genotype-distribution in cervical, vulvar and vaginal disease and genotype-specific prevalence and incidence of HPV infection in females. Infect Agent Cancer 2015; 10: 13.
  • 7. Nezhat FR, Apostol R, Nezhat C et al.: New insights in the pathophysiology of ovarian cancer and implications for screening and prevention. Am J Obstet Gynecol 2015; 213: 262–267.
  • 8. Zeppernick F, Meinhold-Heerlein I: The new FIGO staging system for ovarian, fallopian tube, and primary peritoneal cancer. Arch Gynecol Obstet 2014; 290: 839–842.
  • 9. Brown J, Friedlander M, Backes FJ et al.: Gynecologic Cancer Intergroup (GCIG) consensus review for ovarian germ cell tumors. Int J Gynecol Cancer 2014; 24 (Suppl 3): S48–S54.
  • 10. Banas T, Juszczyk G, Pitynski K et al.: Incidence and mortality rates in breast, corpus uteri, and ovarian cancers in Poland (1980–2013): an analysis of population-based data in relation to socioeconomic changes. Onco Targets Ther 2016; 9: 5521–5530.
  • 11. Zheng G, Yu H, Hemminki A et al.: Familial associations of male breast cancer with other cancers. Breast Cancer Res Treat 2017; 166: 897–902.
  • 12. Reade CJ, McVey RM, Tone AA et al.: The fallopian tube as the origin of high grade serous ovarian cancer: review of a paradigm shift. J Obstet Gynaecol Can 2014; 36: 133–140.
  • 13. Ray-Coquard I, Brown J, Harter P et al.: Gynecologic Cancer InterGroup (GCIG) consensus review for ovarian sex cord stromal tumors. Int J Gynecol Cancer 2014; 24 (Suppl 3): S42–S47.
  • 14. Ness RB, Grisso JA, Klapper J et al.: Racial differences in ovarian cancer risk. J Natl Med Assoc 2000; 92: 176–182.
  • 15. Visser NC, Bulten J, van der Wurff AA et al.: PIpelle Prospective ENDOmetrial carcinoma (PIPENDO) study, pre-operative recognition of high risk endometrial carcinoma: a multicentre prospective cohort study. BMC Cancer 2015; 15: 487.
  • 16. Cărăuleanu A, Lupaşcu IA, Cărăuleanu DM et al.: Clinico-epidemiological study of endometrial hyperplasia – a risk factor for the development of endometrial carcinoma? Rev Med Chir Soc Med Nat Iasi 2015; 119: 154–161.
  • 17. Prameela CG, Ravind R, Gurram BC et al.: Prognostic factors in primary vaginal cancer: a single institute experience and review of literature. J Obstet Gynaecol India 2016; 66: 363–371.
  • 18. Kyrgiou M, Mitra A, Moscicki AB: Does the vaginal microbiota play a role in the development of cervical cancer? Transl Res 2017; 179: 168–182.
  • 19. Yousefi Z, Mottaghi M, Rezaei A et al.: Abnormal presentation of choriocarcinoma and literature review. Iran J Cancer Prev 2016; 9: e4389.
  • 20. World Health Organization: Beira, Mozambique – Ipswich, England. Available from: [cited: September 2016].
  • 21. Johnston C, Ng JS, Manchanda R et al.: Variations in gynecologic oncology training in low (LIC) and middle income (MIC) countries (LMICs): common efforts and challenges. Gynecol Oncol Rep 2017; 20: 9–14.
  • 22. World Health Organization: Screening as well as vaccination is essential in the fight against cervical cancer. Available from: [cited: April 2017].
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