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2017 | 22 | 1 | 5-11
Article title

Alergia na jad pszczeli u pszczelarzy

Content
Title variants
EN
Bee venom allergy in beekeepers
Languages of publication
PL
Abstracts
EN
Beekeepers are a particular group of people highly exposed to stings and allergy to bee venom due to the nature of their work. Positive skin test results or bee venom specific IgE are observed in up to 60% of beekeepers. Reaction to the bee sting occurs most often as a normal local reaction, but a person allergic to bee venom may experience large local reaction, systemic symptoms, including anaphylactic shock. In patients with confirmed systemic allergic reaction in the past, basic diagnostic tests such as skin tests and bee venom specific IgE must be performed. Where appropriate, additional tests such as component- -resolved diagnosis, cell-based assays, tryptase or the venom-specific IgG4 levels should be conducted. Studies have shown significantly higher tryptase and specific IgG4 levels in beekeepers. Moreover, a correlation between clinical symptoms after the sting and the phospholipase A2 specific IgE concentration was observed. During venom-specific immunotherapy, increasing the dose to 200 µg should be considered in beekeepers.
PL
Pszczelarze są szczególną grupą osób najbardziej narażonych na użą- dlenia i alergię na jad pszczeli z racji wykonywanej pracy. Dodatnie wyniki testów skórnych lub obecność swoistych dla jadu pszczelego IgE obserwowane są nawet u 60% badanych pszczelarzy. Reakcja po użądleniu przez pszczołę najczęściej występuje pod postacią normalnej reakcji miejscowej, ale u osoby uczulonej na jad pszczeli może wystą- pić nasilona reakcja miejscowa lub objawy ogólne, do wstrząsu anafilaktycznego włącznie. U pacjentów z reakcją systemową w wywiadzie należy wykonać podstawowe badania diagnostyczne: testy skórne i oznaczenia swoistych dla jadu sIgE, a w uzasadnionych przypadkach badania dodatkowe, takie jak: oznaczenia sIgE dla poszczególnych alergenów jadu pszczelego (diagnostyka komponentowa), testy komórkowe, oznaczanie poziomu tryptazy czy stężenia swoistych dla jadu IgG4. Badania przeprowadzone u pszczelarzy wykazały istotnie wyższe stę- żenia tryptazy oraz swoistych IgG4 w tej grupie zawodowej. Ponadto zaobserwowano korelację nasilenia objawów klinicznych po użądleniu ze stężeniem sIgE dla fosfolipazy A2 . Podejmując decyzję o prowadzeniu swoistej immunterapii jadem pszczelim u pszczelarza należy rozważyć zwiększenie dawki podtrzymującej do 200 µg.
Discipline
Publisher

Year
Volume
22
Issue
1
Pages
5-11
Physical description
Contributors
  • Wydział Medyczny, Państwowa Wyższa Szkoła Zawodowa im. Prezydenta Stanisława Wojciechowskiego w Kaliszu, jkamatysiak@gmail.com
  • Katedra i Zakład Chemii Nieorganicznej i Analitycznej, Uniwersytet Medyczny im. K. Marcinkowskiego w Poznaniu
author
  • Katedra i Zakład Chemii Nieorganicznej i Analitycznej, Uniwersytet Medyczny im. K. Marcinkowskiego w Poznaniu
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article
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bwmeta1.element.psjd-22c7cb98-765d-468d-a568-044ee70af7d3
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