Incidence of intrauterine abnormalities in Pakistani women with unexplained infertility diagnosed via saline infusion sonography

• Authors: Rubina Izhar , Samia Husain

Title variants

PL

Częstość występowania nieprawidłowości wewnątrzmacicznych wśród pakistańskich kobiet z niewyjaśnioną niepłodnością, diagnozowanych z zastosowaniem sonohisterografii

• Languages of publication: EN PL

Abstracts

EN

Objective: To determine the frequency of intrauterine abnormalities in women with unexplained infertility using saline infusion sonography. Material and methods: This was a retrospective cohort study conducted at Aziz medical centre, Karachi, Pakistan between January and December 2015. The study population comprised of women with unexplained infertility who underwent saline infusion sonography as a part of their diagnostic workup. The frequency of uterine abnormalities in these women was determined and the relationship between these pathologies and patient age and body mass index was assessed. Results: Of the 769 women included, 202 (26.3%) had uterine abnormalities. Endometrial polyp (118 cases, 15.3%) was the most common abnormality, followed by submucous fibroids (54, 7%), intrauterine adhesions (20, 2.6%), and septae (10, 5%). Intrauterine pathologies were more common in women with primary infertility (71.8% versus 28.2%, p = 0.002). Uterine abnormalities were most common in the age group 30–34 years (n = 80, 39.6%) and in overweight patients (n = 95, 47%). The distribution of abnormalities differed significantly in various age groups (p = 0.009) and among women with different BMI (p = 0.029). Conclusions: A significant number of women with unexplained infertility present with unsuspected uterine abnormalities; therefore an assessment of the uterine cavity should be performed in all cases.

PL

Cel: Określenie częstości występowania nieprawidłowości wewnątrzmacicznych u kobiet z niewyjaśnioną niepłodnością z zastosowaniem sonohisterografii. Materiał i metody: W ośrodku medycznym Aziz (Karachi, Pakistan) przeprowadzono retrospektywne badanie kohortowe w okresie od stycznia do grudnia 2015 roku. Badana populacja składała się z kobiet z niewyjaśnioną niepłodnością, które w ramach diagnostyki poddano sonohisterografii. Określono częstość występowania nieprawidłowości wewnątrzmacicznych oraz związek między występowaniem patologii a wiekiem i wskaźnikiem masy ciała pacjentek. Wyniki: Spośród 769 kobiet włączonych do badania nieprawidłowości wewnątrzmaciczne stwierdzono u 202 (26,3%) pacjentek. Najbardziej powszechną patologią okazał się polip endometrialny (118 przypadków; 15,3%), a w dalszej kolejności mięśniak podśluzówkowy (54; 7%), zrost wewnątrzmaciczny (20; 2,6%) i przegroda macicy (10; 5%). Nieprawidłowości występowały częściej wśród kobiet z niepłodnością pierwotną (71,8% vs 28,2%, p = 0,002); częściej obserwowano je w przedziale wiekowym 30–34 lata (n = 80; 39,6%) oraz u pacjentek z nadwagą (n = 95; 47%). Rozkład nieprawidłowości różnił się istotnie między poszczególnymi grupami wiekowymi (p = 0,009) oraz między kobietami z różnymi wartościami BMI (p = 0,029). Wnioski: Niepodejrzewane nieprawidłowości wewnątrzmaciczne występują u znacznej liczby kobiet z niewyjaśnioną niepłodnością. W związku z tym we wszystkich przypadkach należy dokonać oceny jamy macicy.

Keywords

EN

infertility workup; intrauterine abnormalities; saline sonography; unexplained infertility

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Communications
• Journal: Journal of Ultrasonography
• Year: 2018
• Volume: 18
• Issue: 74
• Pages: 186–192

Contributors

author

Rubina Izhar

• Department of Gynaecology And Obstetrics, Abbasi Shaheed Hospital & Karachi Medical and Dental College, Karachi, Pakistan

author

Samia Husain

• Department of Gynaecology And Obstetrics, Abbasi Shaheed Hospital & Karachi Medical and Dental College, Karachi, Pakistan

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• Document Type: article