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2014 | 15 | 1 | 32-40

Article title

Poziom współpracy pacjentów chorych na schizofrenię w zakresie przyjmowania leków a ryzyko nawrotu psychozy

Title variants

The level of medication adherence in schizophrenic patients and the risk of psychotic relapse

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Schizofrenia jest przewlekłą chorobą obarczoną wysokim ryzykiem nawrotu. Nowoczesne leczenie schizofrenii, którego istotnym składnikiem jest farmakoterapia może w znacznym stopniu zmniejszyć to ryzyko. Jednak aby leczenie farmakologiczne było skuteczne, konieczna jest dobra współpraca w zakresie wypełniania zaleceń lekarskich ze strony pacjenta. W artykule tym dokonano przeglądu dostępnej literatury dotyczącej powiązań pomiędzy poziomem współpracy w zakresie przyjmowania leków przez pacjentów chorych na schizofrenię a ryzykiem nawrotu psychozy i ponownej hospitalizacji psychiatrycznej. Wychodząc od podstawowych definicji i rozpowszechnienia problemu niestosowania się do zaleceń lekarskich w tej grupie pacjentów, poprzez ukazanie czynników ryzyka wystąpienia tego zjawiska, opisano możliwe powiązania pomiędzy poziomem współpracy pacjentów w zakresie przyjmowania leków a ryzykiem nawrotu psychozy. Dotychczasowe badania wskazują na obecność istotnej zależności pomiędzy poziomem współpracy w zakresie przyjmowania leków przez pacjentów a ryzykiem nawrotu psychozy i rehospitalizacji. Związek ten ma charakter złożony, a duże znaczenie odgrywają czynniki pośrednio związane zarówno z poziomem współpracy przy leczeniu jak i ryzykiem nawrotu schizofrenii.
Schizophrenia is a chronic disease with a high risk of relapse. Modern treatment of schizophrenia that involves pharmacotherapy as its vital element may reduce this risk. However, effective pharmacological intervention requires patient’s compliance with a treatment regimen. This paper provides an overview of the available literature on possible associations between the level of medication adherence in schizophrenic patients and the risk of psychotic relapse and psychiatric rehospitalization. In the first part, the article offers general information on basic concepts, prevalence data and possible factors contributing to nonadherence in schizophrenia. The studies published to date have shown the significant relationship between a level of collaboration with drug treatment by schizophrenic patients and the risk of relapse and rehospitalization. This relationship is complex and largely determined by factors indirectly connected to both the level of medication adherence and the relapse risk.









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