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2013 | 18 | 18 | 181-186
Article title

APPLICATION OF CHITOSAN IN THE FORMULATION OF HYDROGELS APPLIED ON SKIN

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Content
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Languages of publication
EN
Abstracts
EN
These studies concerned the effect of composition on the substrate physicochemical parameters of hydrogels for use on skin. Hydrogels containing 1% of hydrocortisone and 1% of chitosan addition was made on the basis of methylcellulose, sodium carboxymethylcellulose and Carbopol 934 P. The release proceeds according to first-order kinetics. Depending on the type and composition of the polymer gels were obtained with various pharmaceutical availability of hydrocortisone. Addition of 1% chitosan affects the acceleration of the release in any given case.
Publisher

Year
Volume
18
Issue
18
Pages
181-186
Physical description
Contributors
author
  • Faculty of Pharmacy, "Silesian Piasts" memorial Medical University of Wroclaw, jan.meler@am.wroc.pl
References
  • 1. Bialik-Wąs K., Pielichowski K.; (2011) Hydrogel polymer wound dressings for biomedical applications. Czasop. Tech.2-Ch. 10, 39-52
  • 2. Samczewska G, Ciałkowska –Rysz A.; (2006) A comparative studies on the bioavailability of morphine hydrochloride and morphine sulphate in model ointments and hydrogels. Pol.Med. Paliat. 5,3, 94-107
  • 3. 3.Sen M, Yakar A.; ( 2001) Controlled release of antifungal drug terbinafine hydrochloride from poly(N-vinyl 2 –pyrrolidone/ itaconic acid) hydrogels. .Int J Pharm. 228,33-41
  • 4. Kołodziejczyk M.K.; (2004) The subject of investigations was the evaluation of the pharmaceutical availability of naproxen choline salt from a pharmaceutical agent of hydrogel type in in vitro conditions. Farm Pol. 60,442-450
  • 5. Szymanek A, Piotrowska I, Komorowska R, Sieradzki E.; (2007) Formulation of hydrogels with 2,5% ketoprofene content produced on the base of Carbopol 980 and hydroxyprophylmethylcellulose. Farm. Pol. 63, 166-169
  • 6. Zgoda M, Kołodziejska J.;(2008) The polyacrylic acid polymers as modern auxiliary applied in the manufacturing of the pharmaceutical products administered to the skin, suspensions and the bioadhesive forms of a drug with prolonged activity. Farm. Pol. 64,73-83
  • 7. Owczarek A., Pluta J.,Kogut J.; (2010) Evaluation properties of hydrogels with simvastatin prepared on Carbopol 2020. Polim. Med. 40, 57-64
  • 8. Szcześniak M, Pluta J.; (2011) Influence of hydrophiling agents on gel formation Carbopol base. Polym. Med. 41, 2, 27-32
  • 9. Di Colo G, Baggiani A, Mellico G, Cepgi M, Serafini M.F( 2006) A new hydrogels for the extended and complete prednisolone release in the G I tract. I J Pharm. 310:154-161
  • 10. Zgoda M, Musiał B, Iwańczyk B (2003) An influence of hydrogel bases properties on the rate of diffusion of non-steroidal anti-inflammatory drugs onto outside in vitro. Farm. Pol.59:795-802
Document Type
article
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-1c30c19a-1ec9-419c-a9b7-763d14d162c6
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