Introduction. Studies on the dietary habits of depressive patients demonstrate frequent deviation result- ing in the development of many diseases. Purpose. The aim of the study was to assess the efficacy of weight reduction diet in patients with depres- sive disorders, including the assessment of changes in the intake of major nutrients that may promote al- terations in body composition during a three-month observation. Methods. The study included 77 people with excessive body weight (45 women and 32 men; average age of women 49.3±10.3 years and men 47.1± 1.2 years) treated for recurrent depressive disorders and being on a 3-month weight reduction diet. The study patients underwent anthropometric measurements and their body composition was determined with electric bio-impedance. Results. Mean weight loss in women was 2.7±2.5kg, and in men 2.0±5.6kg. There was a decrease in fat mass in women by an average of 1.8±5.7kg and in men by 1.3±7.1kg. A statistically significant reduc- tion was reported in the mean waist circumference (3.8±3.7cm) and hips (2.0 ± 1.9cm) among women. Diet modification brought a decrease in the energy value of daily diet and reduction in the supply of ma- cronutrients. Conclusions. The long-term effect of the nutritional therapy indicates the need for intensified dietary ed- ucation, both in terms of the number of dietary trainings and intensive cooperation between patient and dietician for proper selection of food products. The cooperation should not only be related to diet correc- tion, but is also expected to motivate physical activity and lifestyle changes.