Synthesis, spectral analysis and antimicrobial activity of 2(1H)-quinolinone tethered 1,3,5-triazine derivatives

• Authors: Nikhil P. Savaniya , Amit D. Khakhariya , Priyanka P. Pankhaniya , Kartik D. Ladva
• Languages of publication: EN

Abstracts

EN

A series of novel quinolinone containing 1,3,5-triazine derivatives have been synthesized, characterized and screened for antimicrobial activity. 7-((4-((3-fluoro-4-morpholinophenyl)amino)-6-(arylamino)-1,3,5-triazin-2-yl)oxy)-3,4-dihydroquinolin-2(1H)-one derivatives were prepared by condensation of 7-((4-chloro-6-((3-fluoro-4-morpholinophenyl)amino)-1,3,5-triazin-2-yl)oxy)-3,4-dihydroquinolin-2(1H)-one with differently substituted aniline derivatives. The designed compounds were confirmed via IR, 1H NMR, Mass spectral data. The synthesized compounds checked for their antimicrobial activity using gram-positive bacteria, gram-negative bacteria and fungi against standard drugs.

Keywords

EN

1-3-5-triazine; 3-4-dihydro-2(1H)-quinolinone; Anti-fungal Activity; Antibacterial Activity

Discipline

• BIOCHEMISTRY: BIOCHEMISTRY

• Publisher: Scientific Publishing House „DARWIN”
• Journal: World News of Natural Sciences
• Year: 2024
• Volume: 55
• Pages: 25-32

Contributors

author

Nikhil P. Savaniya

• Department of Chemistry, Government Science College, Ahwa, Dist. Dang-394710, India

author

Amit D. Khakhariya

• Department of Chemistry, Shri M. & N. Virani Science College, Rajkot-360005, India

author

Priyanka P. Pankhaniya

• Department of Chemistry, Shri M. & N. Virani Science College, Rajkot-360005, India

author

Kartik D. Ladva

• Department of Chemistry, Shri M. & N. Virani Science College, Rajkot-360005, India

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• Document Type: article