PL EN


Preferences help
enabled [disable] Abstract
Number of results
2017 | 17 | 68 | 5–16
Article title

Rheumatoid arthritis: what do MRI and ultrasound show

Content
Title variants
PL
Reumatoidalne zapalenie stawów w badaniu MR i ultrasonografii
Languages of publication
EN
Abstracts
EN
Rheumatoid arthritis is the most common inflammatory arthritis, affecting approximately 1% of the world’s population. Its pathogenesis has not been completely understood. However, there is evidence that the disease may involve synovial joints, subchondral bone marrow as well as intra- and extraarticular fat tissue, and may lead to progressive joint destruction and disability. Over the last two decades, significant improvement in its prognosis has been achieved owing to new strategies for disease management, the emergence of new biologic therapies and better utilization of conventional disease-modifying antirheumatic drugs. Prompt diagnosis and appropriate therapy have been recognized as essential for improving clinical outcomes in patients with early rheumatoid arthritis. Despite the potential of ultrasonography and magnetic resonance imaging to visualize all tissues typically involved in the pathogenesis of rheumatoid arthritis, the diagnosis of early disease remains difficult due to limited specificity of findings. This paper summarizes the pathogenesis phenomena of rheumatoid arthritis and describes rheumatoid arthritis-related features of the disease within the synovium, subchondral bone marrow and articular fat tissue on MRI and ultrasound. Moreover, the paper aims to illustrate the significance of MRI and ultrasound findings in rheumatoid arthritis in the diagnosis of subclinical and early inflammation, and the importance of MRI and US in the follow-up and establishing remission. Finally, we also discuss MRI of the spine in rheumatoid arthritis, which may help assess the presence of active inflammation and complications.
PL
Reumatoidalne zapalenie stawów (RZS) jest najczęstszą chorobą zapalną stawów, występującą u ok. 1% populacji światowej(1). Charakteryzuje się zapaleniem błony maziowej oraz zapaleniem kości, które prowadzą do powstania nadżerek kostnych, niszczenia chrząstki stawowej, destrukcji stawu, a co za tym idzie – trwałej niepełnosprawności(2). W ciągu ostatnich 20 lat znacznie poprawiło się rokowanie u chorych na reumatoidalne zapalenie stawów dzięki wprowadzeniu nowych strategii leczenia, zastosowaniu terapii biologicznej i lepszemu wykorzystaniu konwencjonalnych leków modyfikujących przebieg choroby(1). Szybka diagnoza i wdrożenie odpowiedniego leczenia stały się kluczowe dla uzyskania dobrego wyniku leczenia u chorych z wczesnym RZS(1). Artykuł w wersji polskojęzycznej jest dostępny na stronie http://jultrason.pl/wydawnictwa/volume-17-no-68
Discipline
Year
Volume
17
Issue
68
Pages
5–16
Physical description
Contributors
  • Department of Radiology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland; Imaging Diagnostic Department, Warsaw Medical University, Warsaw, Poland
author
  • Department of Radiology, Ghent University Hospital, Gent, Belgium
author
  • Nuffield Orthopaedic Centre, Oxford University Hospitals NHS Trust, Oxford, United Kingdom
References
  • 1. Narváez JA, Narváez J, De Lama E, De Albert M: MR imaging of early rheumatoid arthritis. Radiographics 2010; 30: 143–165.
  • 2. Boutry N, Morel M, Flipo RM, Demondion X, Cotton A: Early rheumatoid arthritis: a review of MRI and sonographic findings. AJR Am J Roentgenol 2007; 189: 1502–1509.
  • 3. Freeston JE, Bird P, Conaghan PG: The role of MRI in rheumatoid arthritis: research and clinical issues. Curr Opin Rheumatol 2009; 21: 95–101.
  • 4. Sudoł-Szopińska I, Jurik AG, Eshed I, Lennart J, Grainger A, Østergaard M et al.: Recommendations of the ESSR Arthritis Subcommittee for the Use of Magnetic Resonance Imaging in Musculoskeletal Rheumatic Diseases. Semin Musculoskelet Radiol 2015; 19: 396–411.
  • 5. Singh JA, Arayssi T, Duray P, Schumacher HR: Immunochemistry of normal human knee synovium: a quantitative study. Ann Rheum Dis 2004; 63: 785–790.
  • 6. Humby F, Bombardieri M, Manzo A, Kelly S, Blades MC, Kirkham B et al.: Ectopic lymphoid structures support ongoing production of classswitched autoantibodies in rheumatoid synovium. PLoS Med 2009; 6: e1.
  • 7. Xu X, Hsu HC, Chen J, Grizzle WE, Chatham WW, Stockard CR et al.: Increased expression of activation-induced cytidine deaminase is associated with anti-CCP and rheumatoid factor in rheumatoid arthritis. Scand J Immunol 2009; 70: 309–316.
  • 8. Walsch DA: Angiogenesis and arthritis. Rheumatology (Oxford) 1999; 38: 103–112.
  • 9. McQueen FM, Benton N, Perry D, Crabbe J, Robinson E, Yeoman S et al.: Bone edema scored on magnetic resonance imaging scans of the dominant carpus at presentation predicts radiographic joint damage of the hands and feet six years later in patients with rheumatoid arthritis. Arthritis Rheum 2003; 48: 1814–1827.
  • 10. Hetland ML, Ejbjerg B, Horslev-Petersen K, Jacobsen S, Vestergaard A, Jurik AG: MRI bone edema is the strongest predictor of subsequent radiographic progression in early rheumatoir arthritis. Results from a 2-year randomized controlled trial (CIMESTRA). Ann Rheum Dis 2009; 68: 384–390.
  • 11. Tamai I, Kawakami A, Uetani M, Takao S, Arima T, Iwamoto N et al.: A prediction rule for disease outcome in patients with undifferentiated arthritis using magnetic resonance imaging of the wrists and fingers joint and serologic autoantibodies. Arthritis Rheum 2009; 61: 772–778.
  • 12. Sudoł-Szopińska I, Kontny E, Zaniewicz-Kaniewska K, Prohorec-Sobieszek M, Saied F, Maśliński W: Role of inflammatory factors and adipose tissue in pathogenesis of rheumatoid arthritis and osteoarthritis. Part I: Rheumatoid adipose tissue. J Ultrason 2013; 13: 192–201.
  • 13. Hodgson RJ, O’Connor P, Moots R: MRI of rheumatoid arthritis image quantitation for the assessment of disease activity, progression and response to therapy. Rheumatology 2008; 47: 13–21.
  • 14. Stomp W, Krabben A, van der Heijde D, Huizinga TW, Bloem JL, van der Helm-van Mil AH et al.: Aiming for a shorter rheumatoid arthritis MRI protocol: can contrast-enhanced MRI replace T2 for the detection of bone marrow oedema? Eur Radiol 2014; 24: 2614–2622.
  • 15. Axelsen MB, Ejbjerg BJ, Hetland ML, Skjødt H, Majgaard O, Lauridsen UB et al.: Differentiation between early rheumatoid arthritis patients and healthy persons by conventional and dynamic contrast-enhanced magnetic resonance imaging. Scand J Rheumatol 2014; 43: 109–118.
  • 16. Østergaard M, Duer A, Møller U, Ejbjerg B: Magnetic resonance imaging of peripheral joints in rheumatic diseases. Best Pract Res Clin Rheumatol 2004; 18: 861–879.
  • 17. van Steenbergen HW, van Nies JA, Huizinga TW, Bloem JL, Reijnierse M, van der Helm-van Mil AH: Characterising arthralgia in the preclinical phase of rheumatoid arthritis using MRI. Ann Rheum Dis 2015; 74: 1225–1232.
  • 18. Krabben A, Stomp W, van Nies AB, Huizinga TWJ, van der Heijde D, Bloem JL et al.: MRI-detected subclinical joint inflammation is associated with radiographic progression. Ann Rheum Dis 2014; 73: 2034–2037.
  • 19. Kroft LJ, Reijnierse M, Kloppenburg M, Verbist BM, Bloem JL, Buchem MA: Rheumatoid arthritis: epidural enhancement as an underestimated cause of subaxial cervical spinal stenosis. Radiology 2004; 231: 57–63.
  • 20. Reijnierse M, Dijkmans BA, Hansen B, Pope TL, Kroon HM, Holscher HC et al.: Neurologic dysfunction in patients with rheumatoid arthritis of the cervical spine. Predictive value of clinical, radiographic and MR imaging parameters. Eur Radiol 2001; 11: 467–473.
  • 21. Reijnierse M, Breedveld FC, Kroom HM, Hansen B, Pope TL, Bloem JL: Are magnetic resonance flexion view useful in evaluating the cervical spine of patients with rheumatoid arthritis? Skeletal Radiol 2000; 29: 85–89.
  • 22. McQueen FM: The MRI view of the synovitis and tenosynovitis in inflammatory arthritis: implications for diagnosis and management. Ann NY Acad Sci 2009; 1154: 21–34.
  • 23. McGonagle D, Hermann KG, Tan AL: Differentiation between osteoarthritis and psoriatic arthritis: implications for pathogenesis and treatment in the biologic therapy era. Rheumatology 2015; 54: 29–38.
  • 24. Stomp W, Krabben A, van der Heijde D, Huizinga TW, Bloem JL, van der Helm-van Mil AH et al.: Are rheumatoids arthritis patients discernible from other early arthritis patients using 1,5T extremity megnetic resonance imaging? A large cross-sectional study. J Rheumatol 2014; 41: 1630–1637.
Document Type
article
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.psjd-0c3f200c-01b1-4b9a-9ead-16e926676731
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.