The International Prenatal Cardiology Collaboration Group – a new concept for global research study

• Authors: Maciej Słodki , Katarzyna Zych-Krekora , Roland Axt-Fliedner , Ana Bianchi , Edward Araujo Junior , Isaac Blickstein , Sefa Kelekci , Lami Yeo , Jay D. Pruetz , Giuseppe Rizzo , Neil Seligman , Mark Sklansky , Luc de Catte , Stuart Weiner , Frank Chervenak , Jader Cruz , Andrii Kurkevych , Michał Krekora , Maria Respondek-Liberska

Title variants

PL

The International Prenatal Cardiology Collaboration Group – nowa idea międzynarodowych badań naukowych

• Languages of publication: EN PL

Abstracts

EN

Congenital heart defects are among the most common congenital defects and contribute substantially to the mortality of newborns and young infants, in spite of well-developed medical and surgical treatments. It is estimated that the mortality of children with congenital heart defects in developing countries is as high as 20%, whereas the incidence of congenital heart defects is approximately 1/100 live births(1). Currently, there is an emphasis on early fetal screening for chromosomal abnormalities and neural tube defects, despite the fact that congenital heart defects are four times more frequent than chromosomal abnormalities and six times more frequent than neural tube defects(2). It should be noted that basic in-utero screening for heart defects is possible as early as the first trimester, which in some cases prompts further work-up and treatment(3). Throughout the world, second trimester screening remains the mainstay of prenatal diagnosis of cardiac anomalies. However, a comprehensive work-up for fetal heart defects can be associated with substantial psychological burden on the mother and her family. Moreover, the prevalence of misdiagnosis can be as high as 36%, thus prompting the need for further training and multidisciplinary team work(4). Furthermore, 33% of heart defects are accompanied by other anomalies(5).

PL

Wrodzone wady serca należą do najczęstszych wad wrodzonych i mimo rozwiniętego leczenia zachowawczego, jak i operacyjnego w dalszym ciągu stanowią jedną z najczęstszych przyczyn zgonów w okresie noworodkowym i wczesnoniemowlęcym. Szacunkowo określa się, że śmiertelność może dotykać około 20% dzieci z wrodzonymi wadami serca w krajach rozwijających się, a każdego roku częstość wrodzonych wad serca oscyluje w granicach 1/100 żywych urodzeń(1). Obecnie uwaga jest kierowana głównie w stronę wczesnej diagnostyki genetycznej, tymczasem wrodzone wady serca są aż 6 razy częstsze od wad chromosomalnych i 4 razy częstsze od wad cewy nerwowej(2). Podstawowa diagnostyka kardiologiczna u płodu jest możliwa już w I trymestrze ciąży i w wybranych przypadkach klinicznych przyczynia się do dalszego postępowania diagnostycznego i terapeutycznego(3). Mimo to w dalszym ciągu podstawowe pozostaje badanie serca płodu w II trymestrze. Kompleksowa diagnoza kardiologiczna płodu niesie ze sobą duże obciążenie psychiczne dla ciężarnej i jej rodziny. Wynika z tego konieczność dalszego szkolenia oraz pracy wielodyscyplinarnej, gdyż – jak pokazują dane z piśmiennictwa – odsetek prenatalnie nieprawidłowo postawionych diagnoz może sięgać nawet 36%(4), a aż 33% wad serca nie jest wadą izolowaną(5).

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Communications
• Journal: Journal of Ultrasonography
• Year: 2016
• Volume: 16
• Issue: 64
• Pages: 94–96

Contributors

author

Maciej Słodki

• Department of Prenatal Cardiology, Polish Mother Memorial Hospital Research Institute, Łódź, Poland

author

Katarzyna Zych-Krekora

• Department of Prenatal Cardiology, Polish Mother Memorial Hospital Research Institute, Łódź, Poland

author

Roland Axt-Fliedner

• Department for Prenatal and Gynecological Sonography, Division of Prenatal Medicine, University of Giessen and Marburg, Germany

author

Ana Bianchi

• Department of Perinatal Medicine University of Montevideo, Uruguay

author

Edward Araujo Junior

• Department of Obstetrics, Federal University of São Paulo, Brazil

author

Isaac Blickstein

• Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, Israel

author

Sefa Kelekci

• Department of Obstetrics and Gynecology, Izmir Katip Çelebi University, Izmir, Turkey

author

Lami Yeo

• Perinatology Research Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, Bethesda, MD and Detroit, MI; Detroit Medical Center, Hutzel Women’s Hospital, Detroit, MI; Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA

author

Jay D. Pruetz

• Division of Pediatric Cardiology, Fetal Cardiology Program, Children’s Hospital Los Angeles, USA

author

Giuseppe Rizzo

• Department of Obstetrics and Gynecology, University of Rome Tor Vergata, Roma, Italy

author

Neil Seligman

• Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Rochester School of Medicine and Dentistry, Rochester, USA

author

Mark Sklansky

• Department of Pediatric Cardiology, UCLA Medical Center, Santa Monica Mattel Children’s Hospital UCLA, Santa Monica, USA

author

Luc de Catte

• Fetal Medicine Department Obstetrics, Gynecology University Hospitals Leuven, Belgium

author

Stuart Weiner

• Division of Reproductive Imaging and Genetics, Jefferson University Hospitals, Philadelphia, USA

author

Frank Chervenak

• Department of Obstetrics and Gynecology, Weill Cornell Medical Center, New York, USA

author

Jader Cruz

• Centro Hospitalar Lisboa Central, Maternidade Dr Alfredo da Costa, Lisboa, Portugal

author

Andrii Kurkevych

• Fetal Cardiology Unit, Ukrainian Children’s Cardiac Center, Kyiv, Ukraine

author

Michał Krekora

• Obstetrics and Gynecology Department, Polish Mother Memorial Hospital Research Institute, Łódź, Poland

author

Maria Respondek-Liberska

• Department of Prenatal Cardiology, Polish Mother Memorial Hospital Research Institute, Łódź, Poland

References

• 1. Simpson LL: Screening for congenital heart disease. Obstet Gynecol Clin North Am 2004; 31: 51–59.
• 2. Ferencz C, Rubin JD, McCarter J, Brenner JI, Neil CA, Perry LW et al.: Congenital heart disease: prevalence at live birth. The Baltimore Washington Infant Study. Am J Epidemiol 1985; 121: 31–36.
• 3. Yagel S, Weissman A, Rotstein Z, Manor M, Hegesh J, Anteby E et al.: Congenital heart defects: natural course and in utero development. Circulation 1997; 96: 550–555.
• 4. Beeri M, Haramati Z, Rein JJ, Nir A: Parental knowledge and views of pediatric congenital heart disease. Isr Med Assoc J 2001; 3: 194–197.
• 5. Frias JL: Genetic issues of congenital heart disease. In: Gessner IH, Victrorica BE (eds.): Pediatric cardiology. Saunders, Philadelphia 1993: 237–242.
• 6. Slodki M, Szymkiewicz-Dangel J, Tobota Z, Seligman NS, Weiner S, Respondek-Liberska M: The Polish National Registry for Fetal Cardiac Pathology: organization, diagnoses, management, educational aspects and telemedicine endeavors. Prenat Diagn 2012; 32: 456–460.
• 7. Sonnenwald DH: Scientific Collaboration. In: B. Cronin (ed.): Annual Review of Information Science & Technology. Vol. 36. Information Today, Medford 2007: 643–681.
• 8. Duysburgh P, Naessens K, Konings W, Jacobs A: Collaboration in a multidisciplinary, distributed research organization: a case study. Higher Education Policy 2012; 25: 267–288.
• 9. NewsRx – News Reporter – Staff News Editor at Heart Disease Weekly: A new study on heart disorders and diseases. Jan. 24, 2016.
• 10. Słodki M: [Prenatal and perinatal management for pregnant women with fetal cardiac defects based on new prenatal cardiac anomalies classification (habilitation thesis)]. University of Lodz, PWSZ Plock 2012.
• 11. Donofrio MT, Rychik J; Fetal Heart Society Governing Board and Steering Committee: Multidisciplinary collaboration in fetal cardiovascular research: the time has come. J Am Soc Echocardiogr 2016; 29: 140–142.

• Document Type: report