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2020 | 147 | 179-196
Article title

Synthesis, biological investigations, QSAR and DFT analysis of sulfonamide chalcones as potential: antimicrobial, antifungal and antimalarial agents

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Abstracts
EN
Various aromatic aldehydes condense with aryl ketone (N-(4-(phenylsulfonamido)phenyl) acetamide) in presence of aqueous alkaline NaOH to form α, β-unsaturated ketone (N-(4-(N-phenylsulfamoyl)phenyl)cinnamamide derivatives or sulfonamide chalcone derivatives). We were synthesized novel sulfonamides chalcones synthesized through Claisen-Schmidt condensation of aromatic aldehydes and sulfonamide containing acetanilide. All the synthesized compounds were characterized using Mass, FTIR, NMR (1H & 13C) spectra analysis. The synthesized sulfonamide chalcone hybrids were screened antimicrobial activity, antifungal and antimalarial activity.
Year
Volume
147
Pages
179-196
Physical description
Contributors
  • Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Rajasthan, India
  • Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Rajasthan, India
  • Department of Chemistry, Faculty of Basic and Applied Science, Madhav University, Rajasthan, India
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article
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YADDA identifier
bwmeta1.element.psjd-0563eeeb-1388-409d-8f45-12ec741ee971
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