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Journal
2018 | 8 | 3 | 76-79
Article title

Acute myocardial infarction in an elderly patient treated for lung cancer

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EN
Abstracts
EN
There is a growing number of elderly patients, so it is necessary to create new standards of oncologic care for such individuals in order to provide them with the best possible treatment. An elderly woman was treated for locally advanced small-cell lung cancer. Due to the suspicion of coronary disease, arterial hypertension and age, anti-cancer treatment with carboplatin and etoposide was recommended. When carboplatin infusion came to a stop, signs of myocardial infarction in ECG as well as elevated levels of troponin I were reported. Originally, non-invasive treatment was introduced, but several days later three DES stents were placed in coronary arteries. An attempt was made to treat the patient with cisplatin and etoposide, after which respiratory failure, tumor lysis syndrome and pancytopenia occurred. That is why chemotherapy was discontinued at the time. The patient’s tumor area and brain was irradiated. 16 months later, she is still alive without signs of disease progression. New oncologic standards should be elaborated in order to ensure appropriate treatment for elderly patients.
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Journal
Year
Volume
8
Issue
3
Pages
76-79
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Contributors
author
  • Department of Medicine and Health Sciences, University of Zielona Góra; Oncology Clinic in Dębno Lubuskie, pplecka@wp.pl
References
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  • 6. Hurria A, Togawa K, Mohile SG et al. Predicting Chemotherapy Toxicity in Older Adults With Cancer: A Prospective Multicenter Study. J Clin Oncol 2011; 29(25): 3457-3465. DOI: 10. 1200/JCO.2011.34.7625.
  • 7. Calvert AH, Newell DR, Gumbrell LA et al. Carboplatin dosage: prospective evaluation of a simple formula based on renal function. J Clin Oncol 1989; 7: 1748.
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  • 9. Berliner S, Rahima R, Sidi Y et al. Acute coronary events following cisplatin-based chemotherapy. Cancer Invest 1990; 8(6): 583-586.
  • 10. Kim ES, Baran AM, Mondo EL et al. Risk of thromboembolism in cisplatin versus carboplatin-treated patients with lung cancer. PLoS ONE 2017; 12(12): e0189410 [online: https://doi.org/10.1371/journal.pone.0189410].
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article
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bwmeta1.element.psjd-00df87ea-2e2b-4e73-9495-d151f58438d5
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