This paper summarizes results of wind tunnel tests of a high-rise building placed in Warsaw city centre. Aerodynamic laboratory studies were accomplished in a boundary layer wind tunnel. The main objective of the research was to determine the distribution of the mean wind pressure coefficient over the building’s external surfaces as affected by the aerodynamic interference between the structure and its immediate city surroundings. Interference coefficients of wind pressure and global wind forces acting upon the surfaces of the building walls and roof were calculated. The aerodynamic studies showed a significant influence of objects located nearby on the wind load that the high-rise building structure surfaces are subjected to.