Antimicrobial coatings as a promising prevention strategy of implants infections triggered by Staphylococcus aureus

• Authors: Mikołaj Malicki , Filip Bielec , Małgorzata Brauncajs , Dorota Pastuszak-Lewandoska

Title variants

PL

Powłoki antybakteryjne jako obiecująca strategia profilaktyczna zakażeń implantów o etiologii Staphylococcus aureus

Abstracts

PL

Postęp technologiczny w tworzeniu różnego typu implantów jest jednym z największych osiągnięć współczesnej chirurgii. Takie urządzenia mogą zastąpić lub przywrócić funkcję uszkodzonych tkanek, co znacząco poprawia jakość i długość życia pacjentów. Niestety infekcje są głównym powodem usuwania implantów. Pacjenci wymagają też zazwyczaj trudnego i kosztownego leczenia. Gronkowiec złocisty jest najczęściej wykrywanym patogenem w tego typu powikłaniach. Powoduje to, że metody profilaktyczne zyskują na atrakcyjności. Najważniejszymi technikami umożliwiającymi zapobieganie infekcjom implantów są pokrycia przeciwdrobnoustrojowe. Dzięki nim biomateriały, z których otrzymywane są urządzenia medyczne mogą uzyskać właściwości antyadhezyjne i bakteriobójcze. W niniejszej pracy dokonujemy przeglądu obiecujących metod tworzenia takich pokryć. Większość koncepcji dotyczy pokrywania implantów substancjami bakteriobójczymi, takimi jak antybiotyki czy nanocząsteczki srebra. Co ciekawe, nawet zmiany w topografii powierzchni mogą być konieczne, aby skutecznie zapobiec adhezji gronkowca złocistego.

EN

Technological progress in the development of various types of implants is one of the greatest achievements of contemporary surgery. Such devices can replace or restore the function of damaged tissues, significantly improving people’s quality of life and its longevity. Unfortunately, infections are the main reason for removing implants from patients who usually then need expensive and challenging treatment. Staphylococcus aureus is the most frequent pathogen detected in such complications. Therefore, prevention methods become more attractive. Antimicrobial coatings are the most important techniques to prevent implant infections. They give the biomaterials from which medical devices are obtained antiadhesive and antibacterial properties. In this paper, we review promising methods of creating such coatings. The majority of concepts are about covering implants with germicidal substances like antibiotics or silver nanoparticles. Interestingly, even changes in the surface topography may be necessary to prevent
Staphylococcus aureus adhesion effectively

Keywords

EN

Staphylococcus aureus; antimicrobial coatings; infections; prevention

PL

Gronkowiec złocisty; powłoki antybakteryjne; profilaktyka zakażeń

• Publisher: Oficyna Wydawnicza Mediton
• Journal: Alergia Astma Immunologia - przegląd kliniczny
• Year: 2023
• Volume: 28
• Issue: 1
• Pages: 2-7

Dates

published

2023

Contributors

author

Mikołaj Malicki

• Department of Microbiology and Laboratory Medical Immunology, Medical University of Lodz, Poland

author

Filip Bielec

• Department of Microbiology and Laboratory Medical Immunology, Medical University of Lodz, Poland

author

Małgorzata Brauncajs

• Department of Microbiology and Laboratory Medical Immunology, Medical University of Lodz, Poland

author

Dorota Pastuszak-Lewandoska

• Department of Microbiology and Laboratory Medical Immunology, Medical University of Lodz, Poland

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Identifiers

Biblioteka Nauki

2215756