Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

PL EN


Preferences help
enabled [disable] Abstract
Number of results
2023 | 95 | 3 | 66-73

Article title

Principles for the use of non-steroidal anti-inflammatory drugs with proton pump inhibitors

Authors

Content

Title variants

Languages of publication

Abstracts

EN
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in numerous areas of medicine. By inhibiting the prostaglandin synthesis pathway, they contribute to the development of injuries to the mucous membranes within the gastrointestinal tract, possibly leading to gastrointestinal bleeding. Proton pump inhibitors (PPIs) are used to prevent such events in high-risk groups. The bleeding risk is highest in patients above the age of 65, patients with a history of gastrointestinal bleeding, and patients with a history of peptic ulcer disease. The efficacy of bleeding prevention could not be proven in other groups. Notably, PPIs are associated with serious side effects, including acute kidney injury, malabsorption syndrome, and osteoporosis. Therefore, recommending the use of PPIs within the framework of prevention should be approached with caution. The widespread belief that IPP should be automatically prescribed together with NSAIDs is false and harmful to patients.

Year

Volume

95

Issue

3

Pages

66-73

Physical description

Dates

published
2023

Contributors

author

References

Document Type

Publication order reference

Identifiers

Biblioteka Nauki
58661475

YADDA identifier

bwmeta1.element.ojs-doi-10_5604_01_3001_0053_7274
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.