Sjögren's syndrome - diagnosis and contemporary therapeutic possibilities

• Authors: Oliwia Cwalina , Ada Pandey , Dominika Prokop , Kinga Czarnacka , Małgorzata Gawlak , Bartosz Kuźlik , Katarzyna Guzek , Ismael Alsoubie , Alicja Chmura-Hołyst , Anna Roszkowska , Ilona Pawlicka , Agnieszka Piskorz , Maciej Kozak

Abstracts

EN

Dry eye syndrome is a group of medical conditions that can be caused by many factors, as a result of which there is an abnormality in moisturizing of the eye surface by a tear film. One of the causes of this disorder is Sjögren’s syndrome, which is an autoimmune disease in which the body produces antibodies against its own proteins. The glands of external secretion, mainly lacrimal and salivary glands are damaged as a result of inflammation. Associated with this side effects, affect negatively and reduce the quality of life, which is why in the following article we present the available therapeutic options for patients suffering from ophthalmological manifestations of Sjögren’s syndrome.

Keywords

EN

Sjögren's syndrome; dry eye syndrome; therapeutic options

• Publisher: Medical Education
• Journal: OphthaTherapy
• Year: 2023
• Volume: 10
• Issue: 2
• Pages: 110-115

Dates

published

2023

Contributors

author

Oliwia Cwalina

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow

• https://orcid.org/0000000270710273

author

Ada Pandey

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow

• https://orcid.org/0000000194671005

author

Dominika Prokop

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow

• https://orcid.org/0000000173187716

author

Kinga Czarnacka

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow

• https://orcid.org/0000000268896507

author

Małgorzata Gawlak

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow

• https://orcid.org/0000000345731379

author

Bartosz Kuźlik

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow

• https://orcid.org/0000000180285525

author

Katarzyna Guzek

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow

• https://orcid.org/0000000317908667

author

Ismael Alsoubie

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow

• https://orcid.org/0000000209743025

author

Alicja Chmura-Hołyst

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow

• https://orcid.org/0000000307331542

author

Anna Roszkowska

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow
• Clinical Ophthalmology Department, Provincial Ophthalmology Hospital in Krakow

• https://orcid.org/0000000280833437

author

Ilona Pawlicka

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow
• Clinical Ophthalmology Department, Provincial Ophthalmology Hospital in Krakow

• https://orcid.org/0000000315567678

author

Agnieszka Piskorz

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow
• Clinical Ophthalmology Department, Provincial Ophthalmology Hospital in Krakow

• https://orcid.org/0000000345530497

author

Maciej Kozak

• Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski Academy in Krakow
• Clinical Ophthalmology Department, Provincial Ophthalmology Hospital in Krakow

• https://orcid.org/0000000179932588

References

• Klippel JH, Dieppe PA, Ferri FF et al. Zespół Sjögrena. In: Szczepański L (ed). Reumatologia. Czelej, Lublin 2000: 233-6.
• Fuglewicz A, Pękala Ł. Wtórny zespół Sjögrena u chorych z układowymi chorobami tkanki łącznej. Adv Clin Exp Med. 2003; 12(3): 329-39.
• Akpek EK, Bunya VY, Saldanha IJ. Sjögren’s Syndrome: More Than Just Dry Eye. Cornea. 2019; 38(5): 658-61. http://doi.org/10.1097/ICO.0000000000001865.
• Kruk K, Rzepakowska A, Osuch-Wójcikiewicz E et al. Zespół Sjögrena – przegląd najnowszych wytycznych diagnostycznych istotnych w praktyce otolaryngologa. Pol Otorhino Rev. 2019: 8(2): 1-6.
• Zimmermann-Górska I, Grzegorz Goncerz G. Zespół Sjögrena (access: 3.11.2022).
• Portal Medycyna Praktyczna. Skala oksfordzka (access: 5.12.2022).
• Akpek EK, Klimava A, Thorne JE et al. Evaluation of patients with dry eye for presence of underlying Sjögren syndrome. Cornea. 2009; 28: 493-7.
• Akpek EK, Mathews P, Hahn S et al. Ocular and systemic morbidity in a longitudinal cohort of Sjogren’s syndrome. Ophthalmology. 2015; 122: 56-61.
• Pieczyński J, Kuklo P. Cyklosporyna A w leczeniu zespołu suchego oka. OphthaTherapy. 2018; 18(2): 85-9. http://doi.org/10.24292/01.OT.290618.04.
• Meyer K. Chemical structure of hyaluronic acid. Fed Proc. 1958; 17: 1075-7.
• Shimmura S, Ono M, Shinozaki K et al. Hialuronian sodu Krople do oczu w leczeniu suchego oka. Fr J Oftalmol. 1995; 79: 1007-11. http://doi.org/10.1136/bjo.79.11.007.
• Yang YJ, Lee WY, Kim YJ et al. A Meta-Analysis of the Efficacy of Hyaluronic Acid Eye Drops for the Treatment of Dry Eye Syndrome. Int J Environ Res Public Health. 2021; 18(5): 2383. http://doi.org/10.3390/ijerph18052383.
• Tsubota K, Goto E, Fujita H et al. Treatment of dry eye by autologous serum application in Sjögren's syndrome. Br J Ophthalmol. 1999; 83(4): 390-5. http://doi.org/10.1136/bjo.83.4.390.
• Bowling E, Russell GE. Topical Steroids and the Treatment of Dry Eye (access: 21.11.2022).
• Yang CQ, Sun W, Gu YS. A clinical study of the efficacy of topical corticosteroids on dry eye. J Zhejiang Univ Sci B. 2006; 7(8): 675-8. http://doi.org/10.1631/jzus.2006.B0675.
• de Paiva CS, Pflugfelder SC, Ng SM et al. Topical cyclosporine A therapy for dry eye syndrome. Cochrane Database Syst Rev. 2019; 9: CD010051. http://doi.org/10.1002/14651858.CD010051.pub2.
• Johnsen SJ, Brun JG, Gøransson LG et al. Risk of non-Hodgkin’s lymphoma in primary Sjögren’s syndrome: A population-based study. Arthritis Care Res. 2013; 65: 816-21.
• Grigoriadou S, Chowdhury F, Pontarini E et al. Review. B-cell depletion with rituximab in the treatment of primary Sjögren’s syndrome: what have we learnt? Clin Exp Rheumatol. 2019; 37(suppl 118): S217-S224.
• Safavi F, Rostami A. Role of serine proteases in inflammation: Bowman-Birk protease inhibitor (BBI) as a potential therapy for autoimmune diseases. Exp Mol Path. 2012; 93: 428-33.
• Joossen C, Baán A, Moreno-Cinos C et al. A novel serine protease inhibitor as potential treatment for dry eye syndrome and ocular inflammation. Sci Rep. 2020; 10: 17268.

Identifiers

DOI

10.24292/01.OT.201523

Biblioteka Nauki

22792621