Effect of Supervised Physical Exercise on Oxidative Stress in Children with Autism

• Authors: Mehrzad Moghadasi , Hamid Arvin , Hassan Rohbanfard , Saeed Arsham , Alireza Ostovar

Abstracts

EN

Background: The etiology of autism spectrum disorders is not well known but oxidative stress has been suggested to play a pathological role. Purpose: The present study aimed to investigate the effects of supervised physical exercise on oxidative stress in children with autism. Methods: Thirty boys with autism (7 to 9 years old) voluntarily participated in this study. They were randomly divided into experimental and control groups. The experimental group performed a physical curriculum known as sports, play and active recreation for kids (SPARK) for 12 weeks (3 sessions of 45 minutes per week), while the control group was exempted to participate in the program. As the clinical parameters, the level of brain-derived neurotrophic factor (BDNF) and malondialdehyde (MDA) were measured before and after the intervention. Results: The results indicated that BDNF levels significantly increased (85.7 %) and MDA concentration significantly decreased (29.2%) in the experimental group (p < 0.05). Conclusions: In conclusion, the supervised physical exercise may result in less oxidative stress in children with autism.

Keywords

EN

exercise training; oxidative stress; BDNF; malondialdehyde; Autism

• Publisher: Uniwersytet Szczeciński. Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
• Journal: Central European Journal of Sport Sciences and Medicine
• Year: 2024
• Volume: 46
• Pages: 45-51

Dates

published

2024

Contributors

author

Mehrzad Moghadasi

• Department of Physical Education, Shiraz branch, Islamic Azad University, Shiraz, Iran

author

Hamid Arvin

• Department of Physical Education, Shiraz branch, Islamic Azad University, Shiraz, Iran

author

Hassan Rohbanfard

• Faculty of Sport Sciences‚ Bu-Ali Sina University‚ Hamedan‚ Iran

author

Saeed Arsham

• Faculty of Physical Education and Sport Sciences‚ Kharazmi University‚ Tehran‚ Iran

author

Alireza Ostovar

• Department of Exercise Physiology, Faculty of Physical Education and Sport Science, University of Guilan, Rasht, Iran

• https://orcid.org/0000000192252675

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Identifiers

DOI

10.18276/cej.2024.2-04

Biblioteka Nauki

47529705