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2014 | 69 |
Article title

A cycle of enzymatic reactions with some properties of neuronal circuits

Content
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EN
Abstracts
EN
A cycle of four methylation and four demethylation reactions with repression or allosteric inhibition of enzymes is considered. The corresponding dynamical system is characterised by two parameters: the sum of reagent concentrations (C) and the ratio of rate constants of forward and backward reactions (k). In a symmetrical case (k=1) the system has a unique equilibrium. At C>4 the equilibrium is unstable and the system has oscillatory solutions. At k essentially different from 1, the system becomes excitable or behaves as a bistable trigger.
Keywords
Year
Volume
69
Physical description
Dates
published
2014
online
22 - 05 - 2015
Contributors
References
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  • Paździoch-Czochra, M., Malarczyk, E. and Sielewiesiuk, J. (2003) Relationship of demethylation processes and cell density in cultures of Rhodococcus erythropolis. Cell Biol. Int. 27, 325-336.
  • Sielewiesiuk, J. and Malarczyk, E. (2002) A cycle of enzymatic reactions that behaves as a neuronal circuit. J. Theor. Biol. 214, 255-262.
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.ojs-doi-10_17951_aaa_2014_69_81
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