Solid acidic FeCl3/Bentonite catalyzed solvent-free condensation: Synthesis, spectral studies and antimicrobial activities of some aryl hydrazine Schiff’s bases

• Authors: Vadamalai Ananthi , Kaliyaraj Rajalakshmi , Inbasekaran Muthuvel , Ganesamoorthy Thirunarayanan
• Languages of publication: EN

Abstracts

EN

Some aryl hydrazide derivatives have been synthesized including 1-(3-chloro-4-nitrophenyl)-2-(3-substituted benzylidene) hydrazines by  FeCl3/Bentonite catalyzed solvent-free  condensation of  substituted phenyl hydrazine and aldehydes under microwave irradiation.  The yields of the hydrazides are more than 70%.  The synthesized hydrazides are characterized by the physical constants, micro analysis and spectroscopic data.  Effect of catalyst,  solvent effect  substituent effect and optimization of the catalyst was studied by the percentage of isolated yields.  From the catalyst optimization, the present study catalyst gave the better yield of products.  The antimicrobial activities of all synthesized of 1-(3-chloro-4-nitrophenyl)-2-(3-substituted benzylidene) hydrazines have been evaluated using Bauer-Kirby disc diffusion method.

Keywords

EN

 

• Publisher: Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
• Journal: Annales Universitatis Mariae Curie-Skłodowska, sectio AA – Chemia
• Year: 2016
• Volume: 71
• Issue: 2

Dates

published

2016

online

03 - 04 - 2017

Contributors

author

Vadamalai Ananthi

author

Kaliyaraj Rajalakshmi

author

Inbasekaran Muthuvel

author

Ganesamoorthy Thirunarayanan

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Identifiers

DOI

10.17951/aa.2016.71.2.127