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2015 | 70 | 2 |
Article title

Synthesis, assessment of substituent effect and antimicrobial activities of some substituted (E)-Nbenzylidene- 5-bromopyridin-2-amines

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EN
Abstracts
EN
A series of substituted (E)-N-benzylidene-5-bromopyridin-2-amine compounds have been synthesized from 5-bromo-2-aminopyridine with different substituted benzaldehydes. The structure of the adducts was confirmed by their physical constants, UV, IR and NMR spectral data. The observed UV absorption maximum λmaxC=N(nm), IR frequencies νC=N(cm-1), The 1H and 13C NMR δ(ppm) chemical shifts values have been correlated with Hammett substituent constants and F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral data has been studied. The antimicrobial activities of all synthesized imines have been studied using Bauer-Kirby method.
Year
Volume
70
Issue
2
Physical description
Dates
published
2015
online
15 - 02 - 2016
References
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.ojs-doi-10_17951_aa_2015_70_2_169
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