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2015 | 70 | 2 |
Article title

Synthesis, spectral correlation analysis and evaluation of biological activities of some substituted hydrazones

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EN
Abstracts
EN
Some novel substituted hydrazone derivatives of amino guanidine have been synthesized with different substituted benzaldehydes by condensation method. The synthesized hydrazones were characterized by their physical constants, UV, IR and NMR spectra. The spectral data have been correlated with Hammett substituent constants and Swain–Lupton parameters. From the result of statistical analysis, the effects of substituents on the spectral data have been predicted. The antimicrobial activities of these synthesized hydrazone compounds have been screened by Bauer-Kirby method using human pathogenic bacteria and fungal species. The antimicrobial activities of all synthesized hydrazone compounds have shown significant activity.
Year
Volume
70
Issue
2
Physical description
Dates
published
2015
online
15 - 02 - 2016
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Document Type
Publication order reference
Identifiers
YADDA identifier
bwmeta1.element.ojs-doi-10_17951_aa_2015_70_2_103
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