PL EN


Preferences help
enabled [disable] Abstract
Number of results
1999 | 14 |
Article title

Znaczenie uwarunkowań genetycznych w dysfunkcjach układu hemostazy w cukrzycy - potencjalne czynniki ryzyka powikłań naczyniowych

Content
Title variants
PL
Significance of genetic po lymorphisms in haemostatic dysfunctions in diabetes mellitus - potential risk factors of vascular complications
Languages of publication
Abstracts
EN
The unambiguous determination of etiopathogenetic factors underlying the increased risk
of vascular disease in diabetic patients remains to be established. Evidence accumulated
hitherto points that such an increased risk might be a constellation of metabolic disorders
and genetic background. Thus, the impairments in coagulation and fibrinolysis, which are
believed to partly result from metabolic disorders encountered in diabetes, and genetic factors
might be compounding in predisposing a diabetic individual to develop the late diabetic
sequelae sooner. The role of the latter seems superior with respect to some dysfunctions in
haemostasis. Hence, the monitoring of the frequency and distribution of genetic polymorphisms
of selected haemostatic proteins might be promising in an attempt to define the reasons of
altered haemostatic imbalance in patients with diabetes mellitus. Based on such a knowledge
one could discriminate the groups of patients with high risk for the development of vascular
disease, in whom pharmacological strategy to attenuate haemostatic impairments would be
desirable.
Keywords
Year
Volume
14
Physical description
Dates
published
1999
References
Document Type
Publication order reference
Identifiers
URI
http://hdl.handle.net/11089/15207
YADDA identifier
bwmeta1.element.hdl_11089_15207
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.