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Title variants
Stimulatory effects of cis- and transplatin on the lipid peroxidation in pig blood platelets
Languages of publication
Abstracts
The effects of cisplatin (cisdiamminedichloroplatinum II) at the concentration of 20 µM
and transplatin (transdiamminedichloroplatinum II) at the concentrations of 20 µM and 200 and transplatin at the concentration of 200 µM were found to cause a significant increase of
thiobarbituric add reactive substances (TBARS).
We have demonstrated, that cisplatin - induced platelet lipid peroxidation was enhanced
by hypertermia and the presence of plasma had no protective effect on dsplatin or transplatin
- stimulated TBARS generation in pig blood platelets. The extracellular GSH (1 mM) protects
against dsplatin - induced lipid peroxidation in blood platelets measured as TBARS.
and transplatin (transdiamminedichloroplatinum II) at the concentrations of 20 µM and 200 and transplatin at the concentration of 200 µM were found to cause a significant increase of
thiobarbituric add reactive substances (TBARS).
We have demonstrated, that cisplatin - induced platelet lipid peroxidation was enhanced
by hypertermia and the presence of plasma had no protective effect on dsplatin or transplatin
- stimulated TBARS generation in pig blood platelets. The extracellular GSH (1 mM) protects
against dsplatin - induced lipid peroxidation in blood platelets measured as TBARS.
Keywords
Publisher
Year
Volume
Physical description
Dates
published
1996
Contributors
References
Document Type
Publication order reference
Identifiers
URI
http://hdl.handle.net/11089/14151
YADDA identifier
bwmeta1.element.hdl_11089_14151
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