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2008 | 4 |
Article title

B-cell chronic lymphocytic leukemia-associated nuclear antigens

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Abstracts
EN
One- and two-dimensional polyacrylamide gel electrophoresis were used to compare
the composition of nuclear polypeptides from normal and В-cell chronic lymphocytic leukemia mononuclear cells. Against two electrophoretically-specific nuclear proteins with molecular weight
of 38/39 and 44/46 kD a from leukemic cells rabbit sera were obtained. As it was analyzed by Western blot technique the available antisera recognized the 38/39 kDa antigen in 53 of the 56
(94.6%), while the 44/46 kDa in 46 of the 49 (93.9%) of examined В-CLL nuclear fraction
preparations, but not in normal ones. The pi values of described leukaemia-specific antigens were
determined; p38/39 had pi in the range of pH 6.55 -7.00 and p44/46 - in the range of pH 6.2-6.4.
Year
Volume
4
Physical description
Dates
published
2008
References
Document Type
Publication order reference
Identifiers
URI
http://hdl.handle.net/11089/12336
YADDA identifier
bwmeta1.element.hdl_11089_12336
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