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Secretory process in blood platelets induced by UVB radiation
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The effects of two doses of UVB radiation (1.08 J/cm2 and 4.32 J/cm2; 1.2 mW/cm2) on
blood platelets secretion of adenine nucleotides and proteins and P selectin expression were
studied. The effect of UVB radiation on P selectin expression (marker of platelet activation)
was compared with the effect of thrombin, which is a strong platelet agonist. The obtained
results showed that exposure of blood platelet to UVB radiation caused the release of adenine
nucleotides, but proteins in a small amount. Moreover, UVB radiation caused decrease of
P selectin expression on blood platelets, in opposite to the effect of thrombin. It seems that
UVB radiation can partly activate blood platelets, but the mechanism is needed to be explain.
blood platelets secretion of adenine nucleotides and proteins and P selectin expression were
studied. The effect of UVB radiation on P selectin expression (marker of platelet activation)
was compared with the effect of thrombin, which is a strong platelet agonist. The obtained
results showed that exposure of blood platelet to UVB radiation caused the release of adenine
nucleotides, but proteins in a small amount. Moreover, UVB radiation caused decrease of
P selectin expression on blood platelets, in opposite to the effect of thrombin. It seems that
UVB radiation can partly activate blood platelets, but the mechanism is needed to be explain.
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2001
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author
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Publication order reference
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http://hdl.handle.net/11089/12048
YADDA identifier
bwmeta1.element.hdl_11089_12048
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