The role of hepatocyte growth factor/c-met interactions in the immune system (p. )

• Authors: G. Skibinski
• Languages of publication: EN

Abstracts

EN

Hepatocyte growth factor (HGF) is a pleiotropic cytokine with mitogenic, motogenic and morphogenic activity for mainly epithelial and endothelial target cells. All the different effects of HGF are mediated through its specific receptor met, a heterodimeric transmembrane tyrosine kinase. The broad activity of HGF and its impact on many physiologic and pathologic processes are reflected by met expression in a variety of organs and cell types. This paper discusses expression of HGF and c-met within the immune system and their interactions in the control of immune cell functions.

Keywords

EN

CELL FUNCTION; HEPATOCYTE GROWTH FACTOR; IMMUNE SYSTEM

Discipline

• IMMUNOLOGY: IMMUNOLOGY

• Publisher: Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Archivum Immunologiae et Therapiae Experimentalis
• Year: 2003
• Volume: 51
• Issue: 5
• Pages: 277-282

Contributors

author

G. Skibinski

• Document Type: REVIEW
• Publication order reference: G. Skibinski, Respiratory Research Group, Department of Clinical Biochemistry, Institute of Clinical Science, Queen?s University of Belfast, Belfast BT12 6BJ, Northern Ireland, UK