Single nucleotide polymorphisms in exon 10 of the chinchilla growth hormone receptor (GHR) gene
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The aim of this study was to detect SNPs in exon 10 of the chinchilla growth hormone receptor gene (GHR) by comparative sequencing. Sixty females of the same breed (Standard) were analysed. Four new SNPs were identified, which cause 3 amino acid substitutions in the intracellular domain of the receptor: G/C at position 135 bp (in relation to the total sequence of exon 10) (gln/his), CAG/AAA at 352 bp and 354 bp (gln/lys), and C/A at 641 bp (thr/asn).
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D. Polasik, Department of Genetics and Animal Breeding, Agricultural University in Szczecin, Judyma 6, 71-466 Szczecin, Poland