Plants as the reactors for production of biopharmaceuticals
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Modern biotechnology is looking for a new source of high quality pharmaceuticals. Interestingly, many of such pharmaceuticals are often natural products provided by plants. An example is a vast array of secondary metabolites. Apart from extraction of these compounds from plant material, many different strategies have been proposed to efficiently produce some of them, using suspension cell cultures. Plants are also a good source of many recombinant proteins, offering a possibility of posttranslational modifications which are limited in prokaryotes. Efficient systems of stable and transient heterologous protein expression for the industrial scale were developed. Here, we briefly introduce such strategies and give examples of different plant products obtained by applying them.
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Marek Figlerowicz, Instytut Chemii Bioorganicznej PAN, Noskowskiego 12/14, 61-704 Poznan, Poland