Specific immunotherapy stimulates the binding of histamine H2 receptor antagonist by lymphocytes

• Authors: Teresa Zak-Nejmark , Jozef Malolepszy , Grazyna Nadobna , Krystyna Kuczynska-Sekieta , Ewa Marczynska-Sarul , Marek Jutel
• Languages of publication: EN

Abstracts

EN

The binding of antagonists of histamine receptors H1 (ranitidine) by perpheral blood lymphocytes from pollinotics was determined before and after the course of immunotherapy. We found that lymphocytes from atopic subjects showed significant decrease in the binding of H2 receptor antagonist as compared to control subjects. specific immunotherapy induced statistically significant increase in H2 receptor antagonist binding, which correlated with the improvement of clinical symptoms.

Keywords

EN

HISTAMINE H2 RECEPTOR; IMMUNOTHERAPY; LYMPHOCYTE

Discipline

• IMMUNOLOGY: IMMUNOLOGY

• Publisher: Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences
• Journal: Archivum Immunologiae et Therapiae Experimentalis
• Year: 1992
• Volume: 40
• Issue: 2
• Pages: 113-116

Contributors

author

Teresa Zak-Nejmark

author

Jozef Malolepszy

author

Grazyna Nadobna

author

Krystyna Kuczynska-Sekieta

author

Ewa Marczynska-Sarul

author

Marek Jutel

• Document Type: article