Regulation of human T lymphocyte potassium channel function by intracellular second messengers ? role of calcium, cyclic AMP and membrane lipid metabolities

• Authors: A. Teisseyre
• Languages of publication: PL

Abstracts

EN

This review focuses on the influence of well-known intracellular second messengers on the activity of potassium channels expressed in human T lymphocytes. Basic biophysical properties of the channels are briefly presented. Available data on the regulatory role of intracellular calcium and cyclic AMP is reviewed. Finally, a possible influence of lipid compounds, especially high-density lipoproteins, lysophospholipids and sphingolipids, on the expression and activity of potassium channels in human T lymphocytes is discussed.

Keywords

EN

CALCIUM; CYCLIC AMP; PATCH CLAMP; POTASSIUM CHANNEL; T LYMPHOCYTE

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2000
• Volume: 54
• Issue: 3
• Pages: 381-390

Contributors

author

A. Teisseyre

• Document Type: ARTICLE
• Publication order reference: A. Teisseyre, Katedra i Zaklad Biofizyki AM, ul. Cha?ubinskiego 10, 50-368 Wroclaw, Poland