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Regulation of human T lymphocyte potassium channel function by intracellular second messengers ? role of calcium, cyclic AMP and membrane lipid metabolities

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EN
This review focuses on the influence of well-known intracellular second messengers on the activity of potassium channels expressed in human T lymphocytes. Basic biophysical properties of the channels are briefly presented. Available data on the regulatory role of intracellular calcium and cyclic AMP is reviewed. Finally, a possible influence of lipid compounds, especially high-density lipoproteins, lysophospholipids and sphingolipids, on the expression and activity of potassium channels in human T lymphocytes is discussed.
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ARTICLE
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A. Teisseyre, Katedra i Zaklad Biofizyki AM, ul. Cha?ubinskiego 10, 50-368 Wroclaw, Poland
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bwmeta1.element.element-from-psjc-f50ce1cd-04bf-3f32-b3cb-b4c5df5fd95e
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