Lipid fractions and fatty acid composition of different organs, viz., digestive gland, mantle, and foot of the gastropod Telescopium telescopium inhabiting estuarine waters of West Bengal, India were studied. Thin layer chromatography and subsequent colorimetric analyses revealed the presence of phospholipid, cholesterol, and, to a lesser extent, triglycerides. Considerable variation in the three classes of lipids was observed in the organs studied so far. Gas liquid chromatography analyses showed the presence of saturated fatty acids (16: 0, 18: 0, 14:0), monoenoics (18:1, 16:1, 20:1), and polyenoic fatty acids (22:5 w6, 20:5 w3, 18:2) in varying amounts in the three organs. This may be related with a specific function of the organ. Polyunsaturated fatty acids are present in fair amounts in T. telescopium. The occurrence of arachidonic acid (20:4) in this gastropod may be related to salinity, as was pointed out by other workers.